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  • Book Reviews

    Wallis, Patrick (2009)

    Compositional shifts in root-associated bacterial and archaeal microbiota track the plant life cycle in field-grown rice

    Edwards, Joseph A.; Santos-Medellín, Christian M.; Liechty, Zachary S.; Nguyen, Bao; Lurie, Eugene; Eason, Shane; Phillips, Gregory; Sundaresan, Venkatesan (2018)
    Projects: NSF | Genomics of Host-Microbiome Interactions in Rice (1444974)
    Bacterial communities associated with roots impact the health and nutrition of the host plant. The dynamics of these microbial assemblies over the plant life cycle are, however, not well understood. Here, we use dense temporal sampling of 1,510 samples from root spatial compartments to characterize the bacterial and archaeal components of the root-associated microbiota of field grown rice (Oryza sativa) over the course of 3 consecutive growing seasons, as well as 2 sites in diverse geographic...

    Impact of Multiplex Polymerase Chain Reaction Testing for Respiratory Pathogen Detection in Pediatric Patients

    Sutton, Courtney C; Walton, Patti J; Williams, Montgomery F; Bastian, Tracey L; Wright, Michael; Spires, S Shaefer (2017)
    Abstract Background Viral pathogens are a leading cause of respiratory infection in the pediatric population. In August 2015, Williamson Medical Center implemented a respiratory panel (RP) that enables rapid detection of 20 common pathogens by multiplex polymerase chain reaction. Utilization of the RP was reviewed to assess the impact of the test on healthcare and antimicrobial utilization. Methods A retrospective chart review was conducted of all patients aged 0 to 17 years with RP specimens...

    Anticonvulsant activity of Dorema ammoniacum gum: evidence for the involvement of benzodiazepines and opioid receptors

    Motevalian, Manijeh; Mehrzadi, Saeed; Ahadi, Samira; Shojaii, Asie (2017)
    This study investigated the anticonvulsant activity and possible mechanism of action of an aqueous solution of Dorema ammoniacum gum (DAG) which has been used traditionally in the treatment of convulsions. In this study, the anticonvulsant activity of DAG was examined using the pentylentetrazole (PTZ) model in mice. Thirty male albino mice were divided randomly and equally to 5 groups, and pretreated with normal saline, diazepam, or various doses of DAG (500, 700, and 1000 mg/kg, i.p.), prior...

    TGF-β1 Is Present at High Levels in Wound Fluid from Breast Cancer Patients Immediately Post-Surgery, and Is Not Increased by Intraoperative Radiation Therapy (IORT)

    Scherer, Sandra D.; Bauer, Jochen; Schmaus, Anja; Neumaier, Christian; Herskind, Carsten; Veldwijk, Marlon R.; Wenz, Frederik; Sleeman, Jonathan P. (2016)
    In patients with low-risk breast cancer, intraoperative radiotherapy (IORT) during breast-conserving surgery is a novel and convenient treatment option for delivering a single high dose of irradiation directly to the tumour bed. However, edema and fibrosis can develop after surgery and radiotherapy, which can subsequently impair quality of life. TGF- β is a strong inducer of the extracellular matrix component hyaluronan (HA). TGF-β expression and HA metabolism can be modulated by irradiation ...
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