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550683 research data, page 1 of 55069

Role of Trehalose in Salinity and Temperature Tolerance in the Model Halophilic Bacterium Chromohalobacter salexigens

The disaccharide trehalose is considered as a universal stress molecule, protecting cells and biomolecules from injuries imposed by high osmolarity, heat, oxidation, desiccation and freezing. Chromohalobacter salexigens is a halophilic and extremely halotolerant γ-proteobacterium of the family Halomonadaceae. In this work, we have investigated the role of trehalose as a protectant against salinity, temperature and desiccation in C. salexigens. A mutant deficient in the trehalose-6-phosphate s...

Model estimates for prime-age adult mortality in Nha Trang, Vietnam.

SE: standard error; DIC: Deviance Information Criterion.

Low CO2 Sensitivity of Microzooplankton Communities in the Gullmar Fjord, Skagerrak: Evidence from a Long-Term Mesocosm Study

Ocean acidification is considered as a crucial stressor for marine communities. In this study, we tested the effects of the IPCC RPC6.0 end-of-century acidification scenario on a natural plankton community in the Gullmar Fjord, Sweden, during a long-term mesocosm experiment from a spring bloom to a mid-summer situation. The focus of this study was on microzooplankton and its interactions with phytoplankton and mesozooplankton. The microzooplankton community was dominated by ciliates, especial...

Biological validation of identified genes.

Wild-type (N2) and mutant C. elegans strains were grown on the four bacterial isolates and absolute fitness (λ) and time to death for 50% of the individuals in a population (TD50 in days) was measured. P-values are shown for contrasts between environments within strain for λ and TD50. Standard error (s.e.m.) is given in parenthesis. + indicates a significant (P

Performance comparisons of TNet-MP and other methods.

Cang, Zixuan; Wei, Guo-Wei (2017)
Publisher: Figshare
Performance comparisons of TNet-MP and other methods.

Enhanced Neutralizing Antibody Titers and Th1 Polarization from a Novel Escherichia coli Derived Pandemic Influenza Vaccine

Influenza pandemics can spread quickly and cost millions of lives; the 2009 H1N1 pandemic highlighted the shortfall in the current vaccine strategy and the need for an improved global response in terms of shortening the time required to manufacture the vaccine and increasing production capacity. Here we describe the pre-clinical assessment of a novel 2009 H1N1 pandemic influenza vaccine based on the E. coli-produced HA globular head domain covalently linked to virus-like particles derived fro...

Valuation of the jumping tests CMJ, SJ and 15 s on the different artificial turf systems.

System 1: Compacted gravel sub-base without elastic layer; System 2: Compacted gravel sub-base with elastic layer; System 3: Asphalt sub-base without elastic layer; System 4: Asphalt sub-base with elastic layer.CMJ = Counter Movement Jump; SJ = Squat Jump; 15 s Test = Fifteen seconds maximal jump test.Data are presented as mean (SD) in 18 soccer players.*Significant differences between pre- and post-RSA (p

Effect of rotenone and malonate on oxygen consumption1.

1All experiments were performed with cardiac tissue homogenates.2Concentrations used: 1 mM malonate, 2 µg/ml rotenone.3Number of individual experiments for each condition. E9.5: 7–9 hearts were pooled per experiment; E11.5 2–3 hearts were pooled per experiment.4NA–not applicable as Cx-1 and -2 substrates do not increase oxygen consumption at E9.5 and thus inhibitors have no effect.Effect of rotenone and malonate on oxygen consumption1.

Honokiol induces superoxide production by targeting mitochondrial respiratory chain complex I in Candida albicans

Sun, Lingmei; Liao, Kai; Wang, Dayong (2017)
Publisher: Figshare
BackgroundHonokiol, a compound extracted from Magnolia officinalis, has antifungal activities by inducing mitochondrial dysfunction and triggering apoptosis in Candida albicans. However, the mechanism of honokiol-induced oxidative stress is poorly understood. The present investigation was designed to determine the specific mitochondrial reactive oxygen species (ROS)-generation component.Methods/resultsWe found that honokiol induced mitochondrial ROS accumulation, mainly superoxide anions (O2•...