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510260 research data, page 1 of 51026

Evaluation of HIV-1 env for compartmentalization between the genital tract and blood using correlation coefficients, Slatkin-Maddison, and Nearest-Neighbor Models.

Notes: Treatment status defined by whether receiving ART, and if so whether ART was “effective”, defined by plasma levels 400 c/mL after the initial 6 months of therapy.a–cViral compartmentalization assessed by Critchlow correlation coefficients (rb and r) [32], the nearest neighbor (Snn) [31] and Slatkin and Maddison (SM) [29].dEvaluation of HIV-1 env compartmentalization between the genital tract and blood with identical sequences collapsed into a single sequence.*Values p

Murine and Bovine γδ T Cells Enhance Innate Immunity against Brucella abortus Infections

γδ T cells have been postulated to act as a first line of defense against infectious agents, particularly intracellular pathogens, representing an important link between the innate and adaptive immune responses. Human γδ T cells expand in the blood of brucellosis patients and are active against Brucella in vitro. However, the role of γδ T cells in vivo during experimental brucellosis has not been studied. Here we report TCRδ−/− mice are more susceptible to B. abortus infection than C57BL/6 mi...

Vaccine efficacy against all episodes of clinical and severe malaria in children aged 5–17 mo at enrollment.

RTS, S Clinical Trials Partnership (2014)
Publisher: Figshare
1Event rate for clinical malaria; affected rate (percent) for severe malaria and hospitalization.2For clinical malaria: p-value from negative binomial regression. For severe malaria, malaria hospitalization, and all-cause hospitalization: p-value from two-sided Fisher's exact test.3Clinical malaria primary case definition: illness in a child brought to a study facility with a measured temperature of ≥37.5°C and P. falciparum asexual parasitemia at a density of >5,000 parasites/mm3 or a case o...

Total antibody positivity rate after single or double immunization.

Note: Mice were randomly assigned to five groups (8/group). Except for the NS and RVJ mock groups, mice received different prime–boost vaccination regimens. Sera were collected 2 weeks after each immunization, and HBV specific antibody was detected by ELISA. Seroconversion is indicated in the table.NS: Normal saline.RVJ: recombinant vaccinia virus.

Spearman's correlation co-efficients between socioeconomic circumstance, early life parameters, hypertension and regional MRI hyperintensity scores.

Abbreviations: aSEC  =  adult socioeconomic circumstance, cSEC  =  childhood socioeconomic circumstance, Edu  =  educational score, CIQ  =  age 11 intelligence, Hyp  =  treated or new hypertension, WMH  =  white matter hyperintensities, PVH  = periventricular hyperintensities, GMH  =  grey matter hyperintensities, ITH  =  infratentorial hyperintensities, ***  = P

Clinical characteristics and gene expression levels of the symptomatic HD patients, PreHD carriers and the controls.

HD: Huntington's Disease. SSRI: selective serotonin uptake inhibitor. UHDRS: The Unified Huntington's Disease Rating Scale. Scale ranges (normal to most severe) include motor score (0 to 124), independence score (100 to 10), and functional capacity (13 to 0).‡: P value of ANCOVA with adjustment of age and gender.*: Statistically significant in comparison with controls, P

Genotype-phenotype-analysis of SNP rs6887695 in patients with Crohn's disease (CD).

PCC:P-value for testing for differences between homozygous carriers of the C allele (C/C) and heterozygous and non-carriers of the C allele. ORCC: corresponding odds ratios and 95% confidence intervals (95% CI). Significant P-values (

Variability of Symbiodinium Communities in Waters, Sediments, and Corals of Thermally Distinct Reef Pools in American Samoa

Reef-building corals host assemblages of symbiotic algae (Symbiodinium spp.) whose diversity and abundance may fluctuate under different conditions, potentially facilitating acclimatization to environmental change. The composition of free-living Symbiodinium in reef waters and sediments may also be environmentally labile and may influence symbiotic assemblages by mediating supply and dispersal. The magnitude and spatial scales of environmental influence over Symbiodinium composition in differ...