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6910 research data, page 1 of 691

Media Ion Composition Controls Regulatory and Virulence Response of Salmonella in Spaceflight

The spaceflight environment is relevant to conditions encountered by pathogens during the course of infection and induces novel changes in microbial pathogenesis not observed using conventional methods. It is unclear how microbial cells sense spaceflight-associated changes to their growth environment and orchestrate corresponding changes in molecular and physiological phenotypes relevant to the infection process. Here we report that spaceflight-induced increases in Salmonella virulence are re...

Summary of properties of the various kinetic models, particularly the Jacobian matrices of the networks.

Jamshidi, Neema; Ø Palsson, Bernhard (2008)
Publisher: Figshare
Pooling of the tiled modal arrays can be classified as complete (in which all elements pools together eventually) or fragmented. The number of conservation pools is equal to the size of the left null space of the Jacobian. The effective dynamic dimensionality is the number of different time scales at which pooling occurs. The time scale span is the ratio of the largest to smallest eigenvalue for each of the networks.

The Identification of Zebrafish Mutants Showing Alterations in Senescence-Associated Biomarkers

There is an interesting overlap of function in a wide range of organisms between genes that modulate the stress responses and those that regulate aging phenotypes and, in some cases, lifespan. We have therefore screened mutagenized zebrafish embryos for the altered expression of a stress biomarker, senescence-associated β-galactosidase (SA-β-gal) in our current study. We validated the use of embryonic SA-β-gal production as a screening tool by analyzing a collection of retrovirus-insertional ...

On the Origin of the Treponematoses: A Phylogenetic Approach

BackgroundSince the first recorded epidemic of syphilis in 1495, controversy has surrounded the origins of the bacterium Treponema pallidum subsp. pallidum and its relationship to the pathogens responsible for the other treponemal diseases: yaws, endemic syphilis, and pinta. Some researchers have argued that the syphilis-causing bacterium, or its progenitor, was brought from the New World to Europe by Christopher Columbus and his men, while others maintain that the treponematoses, including s...

Reversibility of metabolic reactions in the reconstructed networks.

Reversibility of metabolic reactions in the reconstructed networks.

Optical properties of tropospheric aerosol and sulfate scattering efficiency measured at Neumayer Station, Antarctica, supplement to: Weller, Rolf; Lampert, Astrid (2008): Optical properties and sulfate scattering efficiency of boundary layer aerosol at coastal Neumayer Station, Antarctica. Journal of Geophysical Research-Atmospheres, 113, D16208

Weller, Rolf; Lampert, Astrid (2008)
Publisher: PANGAEA - Data Publisher for Earth & Environmental Science
We measured optical properties and ionic composition of the aerosol at Neumayer Station from 2004 through 2006 by an integrating nephelometer and chemical analysis of daily aerosol samples, respectively. From this unique data set we discuss the seasonality of aerosol optical parameters along with their chemical composition. Austral summer (November through March) was characterized by mean particle number concentrations of 472±260 cm**-3 compared to 168±160 cm**-3 during winter (April through ...

A Review of Animal Bone Evidence from Central England

Umberto Albarella; Tessa Pirnie (2008)
Publisher: Archaeology Data Service
The aim of this project was to produce a review of the animal bone evidence from Central England from Mesolithic to Modern times. The dataset collected for this purpose consists of details gleaned from excavation reports (or specialist bone reports), concerning vertebrate remains (of fishes, amphibians, reptiles, birds and mammals) found primarily on archaeological sites. These details include the full bibliographic reference, summary descriptions of each site (for instance, its type, locatio...

[11C]CHIBA-1001 as a Novel PET Ligand for α7 Nicotinic Receptors in the Brain: A PET Study in Conscious Monkeys

BackgroundThe α7 nicotinic acetylcholine receptors (nAChRs) play an important role in the pathophysiology of neuropsychiatric diseases such as schizophrenia and Alzheimer's disease. However, there are currently no suitable positron emission tomography (PET) radioligands for imaging α7 nAChRs in the intact human brain. Here we report the novel PET radioligand [11C]CHIBA-1001 for in vivo imaging of α7 nAChRs in the non-human primate brain.Methodology/Principal FindingsA receptor binding assay s...

Significantly correlated ratios of metabolite concentration with smoker phenotype

Two metabolites M1 and M2 are listed in the first two columns. Pearson's correlation coefficient r of metabolite ratios of M1/M2 and M2/M1 positively and negatively correlated with smoker phenotype are shown in columns 4 and 6, respectively. The corresponding p-values of n-cases of t-tests are indicated in columns 5 and 7, respectively.

Palinustus mossambicus Barnard, 1926 (Crustacea: Decapoda: Achelata: Palinuridae); morphology of the puerulus stage

Clark, Paul F. (2008)
Publisher: Plazi.org taxonomic treatments database
This dataset contains the digitized treatments in Plazi based on the original journal article Palero, Ferran, Guerao, Guillermo, Clark, Paul F. (2008): Palinustus mossambicus Barnard, 1926 (Crustacea: Decapoda: Achelata: Palinuridae); morphology of the puerulus stage. Zootaxa 1857: 44-54, DOI: 10.5281/zenodo.183575