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10785 research data, page 1 of 1079

Social Change and Policy of Taiwanese Indigenous Peoples

Huang, Shu-Min; Chang, Ying-hwa (2009)
Publisher: SRDA - Survey Research Data Archive Taiwan

Ultrafast Energy Transfer in Oligofluorene−Aluminum Bis(8-hydroxyquinoline)acetylacetone Coordination Polymers

Understanding the excited-state dynamics in conjugated systems can lead to their better utilization in optical sensors, organic photovoltaics (OPVs), and organic light-emitting diodes (OLEDs). We present the synthesis of self-assembled coordination polymers comprising two types of fluorescent moieties: discrete fluorene oligomers of a well-defined length (n = 1−9) connected via aluminum(III) bis(8-quinolinolate)acetylacetone joints. Due to their well-defined structure, these materials allowed...

A Groupwise Association Test for Rare Mutations Using a Weighted Sum Statistic

Eskerod Madsen, Bo; R. Browning, Sharon (2009)
Publisher: Figshare
Resequencing is an emerging tool for identification of rare disease-associated mutations. Rare mutations are difficult to tag with SNP genotyping, as genotyping studies are designed to detect common variants. However, studies have shown that genetic heterogeneity is a probable scenario for common diseases, in which multiple rare mutations together explain a large proportion of the genetic basis for the disease. Thus, we propose a weighted-sum method to jointly analyse a group of mutations in ...

Sample sizes for the biological assays used to collect data on the three DiGeorge subjects.

“# cells/RT reaction” is the number of cells used in RNA extraction for spectratyping. The numbers were estimated from the starting number of CD3+ cells and RNA yield. All spectratyping used 150 ng of RNA regardless of the cellular sample size. “CD4+ T cell events” refers to the total number of flow cytometric ...

Validation of 2006 WHO Prediction Scores for True HIV Infection in Children Less than 18 Months with a Positive Serological HIV Test

IntroductionAll infants born to HIV-positive mothers have maternal HIV antibodies, sometimes persistent for 18 months. When Polymerase Chain Reaction (PCR) is not available, August 2006 World Health Organization (WHO) recommendations suggest that clinical criteria may be used for starting antiretroviral treatment (ART) in HIV seropositive children

Force generation of individual day 50 Neor, Puror-selected cardiomyocytes.

CSs were isolated at day 12–13.5 and cultured until day 48 when they were dispersed and deposited onto gelatin-functionalized surfaces of polyacrylamide cast with fluorescent beads and analyzed for force generation at day 50. (A) Diagram of the apparatus containing the polyacrylamide. Platinum electrodes were used to electrically pace the cardiomyocytes at 0.5 Hz with 0.8 ms pulses of 50 volts. Inset shows micrograph of fluorescent beads. Scale bar represents 10 µm. (B) α-actinin immunostaini...

Genome and dif features of a representative panel of proteobacteria.

Carnoy, Christophe; Roten, Claude-Alain (2009)
Publisher: Figshare
(1)The central nucleotide in bold defines the position of the dif sequence on the chromosome. The nucleotides involved in the palindrome are underlined.(2)hyp.prot.  =  dif inserted into a hypothetical protein-encoding gene.(3)Sulfurimonas denitrificans strain DSM 1251  = Thiomicrospira denitrificans ATCC 33889.(4)maximum of the GC skew.

Quantitative Deep Sequencing Reveals Dynamic HIV-1 Escape and Large Population Shifts during CCR5 Antagonist Therapy In Vivo

High-throughput sequencing platforms provide an approach for detecting rare HIV-1 variants and documenting more fully quasispecies diversity. We applied this technology to the V3 loop-coding region of env in samples collected from 4 chronically HIV-infected subjects in whom CCR5 antagonist (vicriviroc [VVC]) therapy failed. Between 25,000–140,000 amplified sequences were obtained per sample. Profound baseline V3 loop sequence heterogeneity existed; predicted CXCR4-using populations were ident...

Association of SNP markers within the linkage disequilibrium block on chromosome 11q24.1 with pathological myopia in Japanese population.

aThe position of markers on chromosome 11 refers to NCBI Build 36.1.bRef. and Var. are the reference and variant nucleotides, respectively, that are defined on the reference sequence of NCBI Build 36.1.cStatistical results using the Mantel-Haenzel method as a fixed-effect model were shown.dOdds ratios (ORs) were calculated for the causative allele (indicated with an asterisk).