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10855 research data, page 1 of 1086

Summary of the effect of different probiotics on animal models of colitis.

Abbreviations used:Disease activity index (DAI).Myeloperoxidase activity (MPO).Manganese superoxide dismutase (MnSOD).Inducible nitric oxide synthase (iNOS).Exopolysaccharide (EPS).Lamina propria mononuclear cells (LPMC).dinitrobenzene sulfonic acid (DNBS).trinitrobenzenesulfonic acid/ethanol (TNBS/E).

Analysis and Quantification of TEM Excretory Cell Images.

Hahn-Windgassen, Annett; R. Van Gilst, Marc (2009)
Publisher: Figshare
High-pressure TEM sections were prepared from young adult animals exposed to control RNAi and nhr-31 RNAi. Images are sorted from sections showing the highest EC diameter to the lowest. For ER abundance, (+) is equal to normal ER abundance, whereas (++) and (+++) represent above normal and much above normal, respectively. (−) indicates below normal ER abundance.

Unconjugated Bilirubin Exposure Impairs Hippocampal Long-Term Synaptic Plasticity

BackgroundJaundice is one of the most common problems encountered in newborn infants, due to immaturity of hepatic conjugation and transport processes for bilirubin. Although the majority of neonatal jaundice is benign, some neonates with severe hyperbilirubinemia develop bilirubin encephalopathy or kernicterus. Accumulation of unconjugated bilirubin (UCB) in selected brain regions may result in temporary or permanent impairments of auditory, motor, or cognitive function; however, the molecul...

Simulations of Tubulin Sheet Polymers as Possible Structural Intermediates in Microtubule Assembly

The microtubule assembly process has been extensively studied, but the underlying molecular mechanism remains poorly understood. The structure of an artificially generated sheet polymer that alternates two types of lateral contacts and that directly converts into microtubules, has been proposed to correspond to the intermediate sheet structure observed during microtubule assembly. We have studied the self-assembly process of GMPCPP tubulins into sheet and microtubule structures using thermody...

Mu insertions in single-copy regions with different epigenetic modifications.

1CHIP-seq of trimethylation of lysine 4 in histone 3 [13].2CHIP-seq of acetylation of lysine 9 in histone 3 [13].3CHIP-seq of trimethylation of lysine 36 in histone 3 [13].4CHIP-seq of trimethylation of lysine 27 in histone 3 [13].5DNA methylation (McrBC sensitive, [13]).6Methylation filtration (hypomethylated, [12]).7Whole genome shotgun (WGS) - genome survey sequences (GSS) as per [66].

IlsA, A Unique Surface Protein of Bacillus cereus Required for Iron Acquisition from Heme, Hemoglobin and Ferritin

The human opportunistic pathogen Bacillus cereus belongs to the B. cereus group that includes bacteria with a broad host spectrum. The ability of these bacteria to colonize diverse hosts is reliant on the presence of adaptation factors. Previously, an IVET strategy led to the identification of a novel B. cereus protein (IlsA, Iron-regulated leucine rich surface protein), which is specifically expressed in the insect host or under iron restrictive conditions in vitro. Here, we show that IlsA i...

Comparative Transcriptional and Translational Analysis of Leptospiral Outer Membrane Protein Expression in Response to Temperature

BackgroundLeptospirosis is a global zoonosis affecting millions of people annually. Transcriptional changes in response to temperature were previously investigated using microarrays to identify genes potentially expressed upon host entry. Past studies found that various leptospiral outer membrane proteins are differentially expressed at different temperatures. However, our microarray studies highlighted a divergence between protein abundance and transcript levels for some proteins. Given the ...

Distribution of bacterial rDNA sequences in catheter samples.

1Numbers designate the percentage of clones in a catheter library that were classified in a phylotype. High values for each specimen are in bold.2Designates whether a patient was subjected to systemic antibiotics during catheterization.3Identified by Blast search of database culled of environmental clones.4Mean BLAST percent identity scores of query sequences to top BLAST hit.5Total number of sequences.6Low abundance clones were removed from table because of space limitations. See Table S1.