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84264 research data, page 1 of 8427

The effectiveness of a mobile application for the development of palpation and ultrasound imaging skills to supplement the traditional learning of physiotherapy students

Abstract Background Mobile learning (m-learning) has becoming very popular in education due to the rapidly advancing technology in our society. The potentials of the mobile applications should be used to enhance the education process. Few mobile applications have been designed to complement the study of physical therapy skills for physiotherapy students. The aim of this study was to investigate whether a mobile application, as a supplement to traditional learning, is useful for physiotherapy ...

Phenology effects on invasion success: insights from coupling field experiments to coexistence theory

Oscar Godoy; Levine, Jonathan M. (2016)
Publisher: Figshare
Ecologists have identified a growing number of functional traits that promote invasion. However, whether trait differences between exotic and native species promote invasion success by enhancing niche differences or giving invaders competitive advantages is poorly understood. We explored the mechanisms by which phenology determines invasion success in a California annual plant community by quantifying how the seasonal timing of growth relates to niche differences that stabilize coexistence, a...

MSC surface markers (CD44, CD73, and CD90) can identify human MSC-derived extracellular vesicles by conventional flow cytometry

Abstract Background Human mesenchymal stromal cells (hMSC) are multipotent cells with both regenerative and immunomodulatory activities making them an attractive tool for cellular therapy. In the last few years it has been shown that the beneficial effects of hMSC may be due to paracrine effects and, at least in part, mediated by extracellular vesicles (EV). EV have emerged as important mediators of cell-to-cell communication. Flow cytometry (FCM) is a routine technology used in most clinical...


Hans Jacquemyn; Rein Brys; Neubert, Michael G. (2016)
Publisher: Figshare
We investigated the effects of fire on population growth rate and invasive spread of the perennial tussock grass Molinia caerulea. During the last decades, this species has invaded heathland communities in Western Europe, replacing typical heathland species such as Calluna vulgaris and Erica tetralix. M. caerulea is considered a major threat to heathland conservation. In 1996, a large and unintended fire destroyed almost one-third of the Kalmthoutse Heide, a large heathland area in northern B...


Understanding evolutionary consequences of intermittent breeding (nonbreeding in individuals that previously bred) requires investigation of the relationships between adult breeding state and two demographic parameters: survival probability and subsequent breeding probability. One major difficulty raised by comparing the demographic features of breeders and nonbreeders as estimated from capture–recapture data is that breeding state is often suspected to influence recapture or resighting proba...

FMAP: Functional Mapping and Analysis Pipeline for metagenomics and metatranscriptomics studies

Jiwoong Kim; Min Kim; Andrew Koh; Yang Xie; Xiaowei Zhan (2016)
Publisher: Figshare
Abstract Background Given the lack of a complete and comprehensive library of microbial reference genomes, determining the functional profile of diverse microbial communities is challenging. The available functional analysis pipelines lack several key features: (i) an integrated alignment tool, (ii) operon-level analysis, and (iii) the ability to process large datasets. Results Here we introduce our open-sourced, stand-alone functional analysis pipeline for analyzing whole metagenomic and met...

Inactivation of MSMEG_0412 gene drastically affects surface related properties of Mycobacterium smegmatis

Abstract Background The outermost layer of mycobacterial cell wall is rich in lipids and glycolipids, surface molecules which differ among species. Mycobacterium smegmatis, an attractive model for the study of both pathogenic and non-pathogenic mycobacteria, presents glycopeptidolipids (GPLs). All the genes necessary for the biosynthesis of such molecules are clustered in a single region of 65 kb and among them, the msmeg_0412 gene has not been characterized yet. Here we report the isolation...

Characterization of a cold-active and salt tolerant esterase identified by functional screening of Arctic metagenomic libraries

Abstract Background The use of metagenomics in enzyme discovery constitutes a powerful approach to access to genomes of unculturable community of microorganisms and isolate novel valuable biocatalysts for use in a wide range of biotechnological and pharmaceutical fields. Results Here we present a novel esterase gene (lip3) identified by functional screening of three fosmid metagenomic libraries, constructed from three marine sediment samples. The sequenced positive fosmid revealed an enzyme o...