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6347 documents, page 1 of 635

Markers of neuroinflammation associated with Alzheimer's disease pathology in older adults.

In vitro and animal studies have linked neuroinflammation to Alzheimer's disease (AD) pathology. Studies on markers of inflammation in subjects with mild cognitive impairment or AD dementia provided inconsistent results. We hypothesized that distinct blood and cerebrospinal fluid (CSF) inflammatory markers are associated with biomarkers of amyloid and tau pathology in older adults without cognitive impairment or with beginning cognitive decline. To identify blood-based and CSF neuroinflamm...

A temporal analysis of vessel type traffic in Istanbul Strait anchorages

A large number of vessels berth in the anchorage areas of the Istanbul Strait on a daily basis for various reasons including bunkering and supply, port operation, lay-up, waiting for Strait passage, and bad weather conditions. These anchorage areas are zoned based on vessel type by maritime authorities where precise considerations need to be made according to the variation in vessel type. In this study, we first present a temporal analysis of vessel type traffic between 2...

Suspended sediment load at the lowermost Ebro River (Catalonia, Spain)

Several attempts to estimate the suspended load and the sediment deficit caused by the reservoirs have been carried out in the lower Ebro River. However, existing data are scarce, scattered along time and space, and obtained under different hydrological conditions and methods. This study estimate the presently suspended sediment load of the lowermost Ebro River, using field data collected during three consecutive years at different verticals of a cross-section and covering a large range of di...

Perspetivas sobre a diversidade cultural: vivências, discursos e representações da interculturalidade

Oliveira, Francine (2016)
Embargo end date: 2019/07/21
Tese de Doutoramento em Ciências da Comunicação (área de especialização em Comunicação Intercultural). Este trabalho tem como objetivo analisar discursos e representações da Interculturalidade e da Diversidade Cultural no contexto do ensino superior português. O percurso de pesquisa compreendeu as seguintes fases: (i) deslindar os conceitos oficiais destes termos e (ii) entrevistar estudantes portugueses e estrangeiros oriundos de países de língua oficial portuguesa a frequentar o...

Reggie-1 and reggie-2 (flotillins) participate in Rab11a-dependent cargo trafficking, spine synapse formation and LTP-related AMPA receptor (GluA1) surface exposure in mouse hippocampal neurons

Reggie-1 and -2 (flotillins) reside at recycling vesicles and promote jointly with Rab11a the targeted delivery of cargo. Recycling is essential for synapse formation suggesting that reggies and Rab11a may regulate the development of spine synapses. Recycling vesicles provide cargo for dendritic growth and recycle surface glutamate receptors (AMPAR, GluA) for long-term potentiation (LTP) induced surface exposure. Here, we show reduced number of spine synapses and impairment of an in vitro cor...

Bir Artistin Ölümü

Taha Toros Arşivi, Dosya No: 34-Nahit Sırrı Örik İstanbul Kalkınma Ajansı (TR10/14/YEN/0033) İstanbul Development Agency (TR10/14/YEN/0033)

Manipulation in games with multiple levels of output

Freixas Bosch, Josep; Parker, Cameron (2015)
Embargo end date: 2018/12/02
In (j,k)-games each player chooses amongst j ordered options and there are k possible outcomes. In this paper, we consider the case where players are assumed to prefer some outcomes to others, and note that when k>2 the players have an incentive to vote strategically. In doing so, we combine the theory of cooperative game theory with social choice theory, especially the theory of single-peaked preferences. We define the concept of a (j,k)-game with preferences and what it means for it to be m...

An empirical assessment of citation information in scientific summarization

Comunicació presentada a la NLDB 2016, 21st International Conference on Applications of Natural Language to Information Systems, celebrada a Salford (Regne Unit) del 22 al 24 de juny del 2016.

Determinants of user demand for lifelong learning in institutions of higher education

The main objective of this study is to identify the determinants that influence user demand for lifelong learning in institutions of higher education. Qualitative methodology was used to develop an instrument and a quantitative approach was used for the remainder of the study. After a literature review and in-depth interviews with experts in lifelong learning, we obtained the dimensions of the study and validated a questionnaire using expert opinion and a pilot test. The results and conclusio...

Investigating the combined impact of plasticizer and shear force on the efficiency of low temperature reclaiming of ground tire rubber (GTR)

In the present work, ground tire rubber (GTR) was mechano-chemically reclaimed at ambient temperature using two-roll mills. Road bitumen and styrene-butadiene-styrene (SBS)-modified bitumen at variable content (in range: 2.5-20 phr) were applied as reactive plasticizers to enhance reclaiming of GTR. For better understanding the plasticizing effect of bitumen on the quality of obtained reclaimed rubber, mechano-chemically reclaimed GTR has been compared with GTR after thermo-mechanical reclaim...