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11100466 documents, page 1 of 1110047

A case of intermittent explosive disorder

A case of impulse control disorder was observed and managed. In this case, the serving soldier of the Indian army presented with explosive outbursts of extreme violence and anger, which was not clearly directed. Following this act of aggression, he would experience a sense of gratification and relief. The episodes were recurrent and resulted in assaults or destruction of property. The aggression displayed was out of proportion to any perceived provocation and the individual felt increasing te...

Comparative analysis of budesonide/formoterol and fluticasone/salmeterol combinations in COPD patients: findings from a real-world analysis in an Italian setting [Corrigendum]

Perrone V, Sangiorgi D, Buda S, Degli Esposti L. Int J Chron Obstruct Pulmon Dis. 2016;11:2749–2755. On page 2749, Patients and methods section, line 5, “between January 1, 2009 and December 31, 2011 (inclusion period)” should have read “between January 1, 2010 and December 31, 2011 (inclusion period)”. On page 2750, Cohort definition section, line 4, “between January 1, 2011 and December 31, 2011 (inclusion period)” should have read “...

Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling

eLife digest The cell cycle is the process by which a cell divides to produce two near-identical daughter cells. Two crucial parts of the cell cycle are the duplication of the chromosomes in the original cell, and the segregation of these chromosomes between the two daughter cells. These and other parts of the cell cycle are strictly regulated to prevent errors, which can lead to cancer and other diseases. After chromosome duplication has taken place, the pairs of identical chromosomes, known...

The engineer Hrista Stamenkovic proposal for triangular reinforcement of support walls

This paper presents and a brief overview of Mr Hrista Stamenkovic's proposal of the triangular reinforcement in supporting walls exposed to horizontal forces (earthquake, wind). The reinforcement triangular allows total exploitation of reinforcement in compression and tension, is that, the most rational and the most economical design with the highest degree of safety will be achieved.

Living with Malignant Wound in Cancer Patients and Adolescents with Non- Cancer Diagnosis: a Meta-Synthesis of Qualitative Studies

Background Malignant wound causes a devastating physical and psychological condition in cancer patients. This study presents a review which can provide better insights into the life of cancer patients living with malignant wound. The aim of this meta-synthesis was to analyze and synthesize findings from qualitative studies of the lived experiences of patients with malignant wound. Materials and Methods This meta-synthesis followed the Sandelowski and Barroso’s guideline and was designed to sy...

Food Patterns, Lifestyle, and Hypertension

High blood pressure (BP) is considered as a strong predisposing factor for cardiovascular diseases (CVD) Environmental and genetic factors may have a role in high blood pressures. Nutrition has a potential role in the prevention of hypertension and its sequelae. Effect of lowering blood pressure by modification of complex dietary patterns may be the result of synergism between the various components of certain foods or food combinations rather than of the specific effect of a particular nutri...

The absence of dystrophin brain isoform expression in healthy human heart ventricles explains the pathogenesis of 5' X-linked dilated cardiomyopathy

Abstract Background In X-linked dilated cardiomyopathy due to dystrophin mutations which abolish the expression of the M isoform (5'-XLDC), the skeletal muscle is spared through the up-regulation of the Brain (B) isoform, a compensatory mechanism that does not appear to occur in the heart of affected individuals. Methods We quantitatively studied the expression topography of both B and M isoforms in various human heart regions through in-situ RNA hybridization, Reverse-Transcriptase and Real-...

A posteriori error estimator based on gradient recovery by averaging for convection-diffusion-reaction problems approximated by discontinuous Galerkin methods

International audience; We consider some (anisotropic and piecewise constant) convection-diffusion-reaction problems in domains of R2, approximated by a discontinuous Galerkin method with polynomials of any degree. We propose two a posteriori error estimators based on gradient recovery by averaging. It is shown that these estimators give rise to an upper bound where the constant is explicitly known up to some additional terms that guarantees reliability. The lower bound is also established, o...

TEN KEY CONCEPTS AND THE SUCCESS OF ROMANIAN ORGANIZATIONS

This paper is focused on ten key concepts which influence the success of the organizations at the beginning of XXI century. The great changes generated by globalization determine firms to be more competitive. This means that we have to focus on: mission, leadership, emotional intelligence, innovation, organizational culture, human resources, total quality management, ethics, conflict management, brand, and the value offered to the clients.