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Macedonian Journal of Medical Sciences
175 Publications
collected from a compatible aggregator


  • Syntheses, Characterization and In-Vitro Anti-Inflammatory Activity of Some Novel Thiophenes

    Deka, Satyendra; Mohan, Shamanna; Saravanan, Janardhan; Kakati, Manoj; Talukdar, Apurba; Sahariah, Bhargab Jyoti; Dey, Biplab Kumar; Sarma, Rama Kanta (2012)
    Aim: The present study was aimed to synthesize a series of 2-substituted benzylidine imino-3-(3-chloro-4-fluorophenyl)-carboxamido-4,5-trimethylene thiophenes SPJ-1(a-m) and to evaluate their in-vitro anti-inflammatory activity.Materials and Methods: The starting material (SPJ-1) was prepared by the application of versatile Gewald reaction. The In-vitro anti-inflammatory activity of synthesized compounds [SPJ-1(a-m)] was evaluated using inhibition of bovine serum albumin denaturation method.R...

    Can Statins Help „Good Cholesterol“ to Become Even Better

    Iric-Cupic, Violeta; Milanov, Srdjan; Davidovic, Goran; Zdravkovic, Vladimir; Vuckovic-Filipovic, Jelena; Vucic, Rada; Simic, Ivan (2013)
    Background: Ischemic heart disease (IHD) is a most common manifestation of generalised atherosclerosis. Hyperlipidemia is one of the most significant risk factors causing atherosclerosis. Becouse of this, statin therapy is the ²guideline² in therapy of hyperlipoproteinemia.Aim: The aim of this study was to show the hypolipemic effect of statins.Material and Methods: The research included 74 patients with hyperlipoproteinemia type II and III, with (59 patients) or without (15) coronary disease...

    Proposal for Improved Translation and Meaning of “Public Health” in the Republic of Macedonia

    Lazarevik, Vladimir; Donev, Doncho (2017)
    The translation and use of the term "public health" in the Republic of Macedonia creates confusions among students, professionals and the public. Its use and meaning in Macedonian language is associated more to the ownership over the healthcare system by the state, rather than to explain the primary goal and mission of public health to protect, promote and restore the health of the public. There is a need to clarify, change and standardize the use of this terminology in the Republic of Macedo...

    Screening of BRCA1 Mutations Using C-terminal Antibody in Sporadic non Familial Colonic Carcinoma

    Esmail, Reham Sh.; Sharaf, Walid M.; Helmy, Noha A.; Farrag, Abdel Razik H.; Badawi, Manal A.; Gamal Eldin, Amina A. (2014)
    Background: Cancer colon is one of the most prevalent cancers in Egypt. Sporadic cancer colon is much more common than familial type; the latter accounting for not more than 30% of the reported cases in different registrations. BRCA1 is a tumor suppressor gene which is proved to be mutated in many cancer types. Limited studies tried to screen its mutation in cancer colon.Aim: This work is aimed to screen BRCA1 mutations using C-terminal antibody in sporadic non familial colonic carcinoma.Subj...

    Electrophysiological Evaluation of the Incidence of Martin-Gruber Anastomosis in Healthy Bosnian Population

    Hodzic, Renata; Piric, Nermina; Hodzic, Mirsad; Kojic, Biljana (2011)
    Background: Martin-Gruber anastomosis (MGA) is the well known anostomosis that occur at the various levels between the median and ulnar nerves. This anastomosis involves axons leaving either the main trunk of median nerve or the anterior interosseous nerve, crossing through the forearm to join the ulnar nerve. Knowledge of the incidence of this anastomosis is necessary because MGA can cause confusion in the assesment of nerve injuries and compressive neuropathies.Aim: We aimed to assess the o...
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