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Name
Experimental Biomedical Research
Type
Journal
Items
17 Publications
Compatibility
OpenAIRE Basic (DRIVER OA)
OAI-PMH
http://experimentalbiomedicalresearch.com/ojs/index.php/ebr/oai

 

  • Protective effects of cordycepin on the histopathological changes and oxidative stress induced by hepatic ischemia/reperfusion in rats

    Okur, Mehmet Hanifi; Zeytun, Hikmet; Basuguy, Erol; Aydogdu, Gulay; Alabalık, Ulas; Kaplan, Ibrahim; Akdeniz, Sevinc; Arslan, Serkan; Aydoğdu, Bahattin (2018)
    Aim: To investigate the effects of cordycepin on the histopathological changes and oxidative stress induced by hepatic ischemia/reperfusion (I/R) in rats. Method: Forty male Wistar rats were randomly divided into 4 groups as group I (sham, n=10), group II (control, n=10), group III (I/R-untreated, n=10) and group IV (I/R-cordycepin, n=10). Liver ischemia was induced for 30 min then reperfusion was allowed for 1 h. At the end of the experiment, liver specimens and blood samples were taken f...

    Patients’ misperception regarding the difficulty of lumbar puncture

    Ogun, Muhammed Nur; Onerli, Merve (2018)
    Aim: Lumbar puncture (LP) is a crucial method of diagnosis and treatment of neurological diseases. Despite its importance, the patients' refusal of the procedure leads to difficulties in diagnosis and treatment. One of the main reasons for patients’ refusal may be that LP is perceived to be more difficult than it actually is. Our aim was to investigate whether the patients had prejudices against the difficulty of LP treatment. Methods: Sixty-seven patients aged between 20 and 80 years were...

    Mean Platelet Volume to Platelet ratio as a promising marker of hepatosteatosis

    Kosekli, Mehmet Ali; Erkus, Edip; Kocak, Mehmet Zahid (2018)
    Aim: Hepatosteatosis confers increased lipid accumulation in the hepatocytes which is associated with inflammation. Hemogram parameters, such as mean platelet volume (MPV) and MPV to platelet ratio (MPR) are proposed as novel inflammatory markers in recent studies. We aimed to compare MPR of subjects with hepatosteatosis to those in healthy controls. Methods: Patient admissions to our clinic with a diagnosis of hepatosteatosis were retrospectively analyzed MPR values compared to those in h...

    Evaluation of retinal nerve fiber layer and ganglion cell layer thicknesses with optical coherence tomography in patients with vitamin B12 deficiency

    Dogan, Umit; Turkoglu, Sule Aydın; Ulas, Fatih; Soydan, Adem; Kaymaz, Abdulgani; Eroglu, Tarik; Agca, Sumeyra (2018)
    Aim: We aimed to compare the retinal nerve fiber layer (RNFL) and ganglion cell layer (GCL) thickness of B12 vitamin deficiency patients with healthy controls using optical coherence tomography (OCT). Methods: Forty-six patients (27 females / 19 males) diagnosed with B12 vitamin deficiency and 46 healthy controls (26 females / 20 males) with similar age and sex were included in the study. RNFL thickness of global, superotemporal, temporal, inferotemporal, superonasal, nasal and inferonasal...

    Effects of the phosphodiesterase type-5 inhibitor tadalafil on nociception, morphine analgesia and tolerance in rats

    Taskiran, Ahmet Sevki; Ozdemir, Ercan; Arslan, Gokhan; Tastemur, Yasar; Filiz, Ahmet Kemal (2018)
    Aim: Tadalafil is a potent, selective and reversible inhibitor of phosphodiesterase type 5 (PDE5) enzyme breakdowning cyclic guanosine monophosphate (cGMP). In this study, we aimed to investigate the effects of tadalafil on nociception, morphine analgesia and tolerance. Methods: In this study, 54 Wistar Albino (230-250 g) male rats were used. First of all, four different doses (2, 4, 8, 16 mg/kg) were used to determine the optimum effective dose of tadalafil on nociception. Optimum ac...
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