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Unitn-eprints PhD
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1523 Publications
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  • Characterization of Small Molecules Inhibiting the RNA Binding Protein HuR

    Lal, Preet (2017)
    HuR, the ubiquitously expressed member of the ELAV (embryonic lethal abnormal vision) family of RNA binding proteins, selectively binds to AREs (AU-rich elements) and mainly stabilizes ARE-containing mRNAs, e.g. TNFα, VEGF, c-FOS, favoring specific protein translation. TNFα mRNA is one of the most important target mRNA of HuR since the protein encoded by this gene mediates the inflammatory response and its overexpression is correlated with autoimmune diseases and cancer-related inflammation. ...

    La condizione liminale della consulenza: racconti di lavoro tra autonomia e organizzazione

    Maestripieri, Lara (2011)
    La tesi in oggetto analizza l'identità professionale della consulenza di management in Italia al fine di identificare le modalità attraverso le quali questi lavoratori esplicitano il proprio professionalismo nel discorso. A ciò si aggiunge l’interesse di studiare quali conseguenze ha in termini di welfare, diritti e riconoscimento sociale della loro attività il fatto che, sebbene siano professionisti di fatto, non siano compresi dal sistema formale delle professioni, ancora incentrato sul mod...

    The Development of socio-moral Evaluations in human Infants and Preschoolers

    Neira-Gutiérrez, Isabel Cristina (2015)
    I will be presenting some empirical findings on the development of socio-moral evaluations in infants and preschoolers, this subject has had a long trajectory in the field of psychology in the last decades. For this reason, it is important that I describe some of the classical theories and recent literature that explains the development of morality. More specifically, I studied next to my collaborators: the emerging capacity of ‘the sense of fairness’, ‘harm’, ‘prosocial helping behaviors’, ...

    Ground state and dynamical properties of many-body systems by non conventional Quantum Monte Carlo algorithms

    Roggero, Alessandro (2014)
    In this work we develop Quantum Monte Carlo techniques suitable for exploring both ground state and dynamical properties of interacting many-body systems. We then apply these techniques to the study of excitations in superfluid He4 and to explore the structure of nuclear systems using chiral effective field theory interactions.

    Protein-dependent prediction of messenger RNA binding using Support Vector Machines

    Livi, Carmen Maria (2013)
    RNA-binding proteins interact specifically with RNA strands to regulate important cellular processes. Knowing the binding partners of a protein is a crucial issue in biology and it is essential to understand the protein function and its involvement in diseases. The identification of the interactions is currently resolvable only through in vivo and in vitro experiments which may not detect all binding partners. Computational methods which capture the protein-dependent nature of the binding phe...
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