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Scientific documents from the Saarland University
Institutional Repository
6118 Publications
OpenAIRE 3.0 (OA, funding)
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  • Finding regions of aberrant DNA copy number associated with tumor phenotype

    Tolosi, Laura (2012)
    DNA copy number alterations are a hallmark of cancer. Understanding their role in tumor progression can help improve diagnosis, prognosis and therapy selection for cancer patients. High-resolution, genome-wide measurements of DNA copy number changes for large cohorts of tumors are currently available, owing to technologies like microarray-based array comparative hybridization (arrayCGH). In this thesis, we present a computational pipeline for statistical analysis of tumor cohorts, which can h...

    Definition von Problemklassen im Maschinenbau als eine Begriffsbildungsaufgabe

    Reinartz, Thomas (1991)
    Experten bilden, zum Beispiel im Bereich des Maschinenbaus, zu einer Menge von Problemstellungen ihrer Domäne Problemklassen. Die Erstellung solcher Problemklassen kann als Aufgabe der menschlichen Begriffsbildung angesehen werden. Gemeinsam mit den Begriffen der Problemklassen werden allgemeine Lösungsstrategien, die auf theoretischem Wissen der Domäne basieren, entwickelt und mit dem zugehörigen Begriff assoziiert, so daß die Begriffe die Lösung neuer Problemstellungen leiten. Eine Aufgabe ...

    Two methods of obtaining sol gel Nb2O5 thin films for electrochromic devices

    Avellaneda, César O.; Pawlicka, Agnieszka; Aegerter, Michel A. (1998)
    Nb2O5 coatings prepared by the sol-gel route using the dip coating technique with sols prepared from alkoxide or chloroalkoxide (two different methods: sonocatalytic and conventional) precursors are a promising alternative for WO3 electrochromic coatings. The crystalline films (TT phase) sintered at 560 and 600 degrees C are transparent and present a deep blue colour under Li+ ion insertion. Electrochemical stability is excellent as these systems are fully reversible and stable and no change ...

    New lower bounds for Hopcroft´s problem

    Erickson, Jeff (1994)
    We establish new lower bounds on the complexity of the following basic geometric problem, attributed to John Hopcroft: Given a set of n points and m hyperplanes in \mathbb{R}^{d}, is any point contained in any hyperplane? We define a general class of partitioning algorithms, and show that in the worst case, for all m and n, any such algorithm requires time \Omega(n\log m+n^{2/3}m^{2/3}+m\log n) in two dimensions, or \Omega(n\log m+n^{5/6}m^{1/2}+n^{1/2}m^{5/6}+m\lo...
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