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Oxford University Research Archive
Institutional Repository
13873 Publications
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  • Cuprizone demyelination induces a unique inflammatory response in the subventricular zone.

    Hillis, JM; Davies, J; Mundim, MV; Al-Dalahmah, O; Szele, FG (2016)
    BackgroundCuprizone leads to demyelination of the corpus callosum (CC) and activates progenitor cells in the adjacent subventricular zone (SVZ), a stem cell niche which contributes to remyelination. The healthy SVZ contains semi-activated microglia and constitutively expresses the pro-inflammatory molecule galectin-3 (Gal-3) suggesting the niche uniquely regulates inflammation. MethodsWe studied the inflammatory response to cuprizone in the SVZ and CC in Gal-3 knockout mice using immunohis...

    Unseen professional learning mediated by networked technology in an academic context

    Jingjing Zhang
    Recent technological advances are providing new and exciting opportunities for researchers to work together across the conventional boundaries of time, distance, and discipline. These advances have formed new networks of research, both in electronic mediums and in face-to-face environments, different from traditional networks in terms of their changing nature and scope. Such networks potentially provide rich opportunities for informal and unplanned professional learning of academics involved ...

    Models for polythermal ice sheets and glaciers

    Hewitt, Ian; Schoof, C (2016)
    Polythermal ice sheets and glaciers contain both cold ice and temperate ice. We present two new models to describe the temperature and water-content of such ice masses, accounting for the possibility of gravity- and pressure-driven water drainage according to Darcy's law. Both models are based on the principle of energy conservation; one additionally invokes the theory of viscous compaction to calculate pore water pressure, and the other involves a modification of existing enthalpy gradient m...

    Using an imperfect photonic network to implement random unitaries

    Burgwal, R; Clements, WR; Smith, DH; Gates, JC; Kolthammer, WS; Renema, JJ; Walmsley, IA (2017)
    We numerically investigate the implementation of Haar-random unitarity transformations and Fourier transformations in photonic devices consisting of beam splitters and phase shifters, which are used for integrated photonics implementations of boson sampling. The distribution of reflectivities required to implement an arbitrary unitary transformation is skewed towards low values, and this skew becomes stronger the larger the number of modes. A realistic implementation using Mach-Zehnder interf...

    Cost of hemodialysis in a public-sector tertiary hospital of India

    Kaur, G; Prinja, S; Ramachandran, R; Malhotra, P; Gupta, KL; Jha, V (2018)
    Introduction Nearly 220 thousand patients are diagnosed with End Stage Renal Disease (ESRD) 33 every year, which calls for an additional demand for 34 million dialysis sessions in India. The Government of India has announced a National Dialysis Program to provide for free dialysis in public hospitals. In this paper, we estimate the overall cost of performing hemodialysis (HD) in a tertiary care hospital. Secondly, we also assess the catastrophic impact of out of pocket expenditure for hemo...
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