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8921 Publications
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  • Microenvironment dependent gene expression signatures in reprogrammed human colon normal and cancer cell lines

    Strainienė, Eglė; Binkis, Mindaugas; Urnikytė, Silvija; Stankevičius, Vaidotas; Sasnauskienė, Aušra; Kundrotas, Gabrielis; Kazlauskas, Andrius; Sužiedėlis, Kęstutis (2018)
    Background: Since the first evidence suggesting existence of stem-like cancer cells, the process of cells reprogramming to the stem cell state remains as an attractive tool for cancer stemness research. Current knowledge in the field of cancer stemness, indicates that the microenvironment is a fundamental regulator of cell behavior. With regard to this, we investigated the changes of genome wide gene expression in reprogrammed human colon normal epithelial CRL-1831 and colon carcinoma DLD1 ce...

    Transitivity pairs in Baltic: between Finnic and Slavic

    Nau, Nicole; Pakerys, Jurgis (2017)
    In this paper we examine transitivity pairs in the two modern Baltic languages Lithuanian and Latvian and compare them to neighbouring Finnic (Finnish, Estonian) and Slavic (Russian, Polish) languages. In Slavic the main strategy is to derive the intransitive (noncausal) verb from the transitive (causal) verb, while in Finnic we nd a high number of derived causatives. Baltic uses both techniques, and in addition, there is a higher number of pairs where either both verbs are marked, or two et...

    A scoping review of ICD-11 adjustment disorder research

    Kazlauskas, Evaldas; Želvienė, Paulina; Lorenz, Louisa; Quero, Soledad; Maercker, Andreas (2018)
    Background: Adjustment disorder (AjD) is one of the most used mental disorder diagnoses among mental health professionals. Important revisions of the AjD definition in the 11th edition of the International Classification of Diseases (ICD-11) are proposed. AjD is included in a chapter of disorders specifically associated with stress in ICD-11. Objective: This paper aims to review recent developments in ICD-11 AjD research, and to discuss the available ICD-11 AjD diagnosis validation studies, A...

    Vaisiaus uždegiminio atsako sindromo įtaka neišnešioto naujagimio psichomotorinei raidai atskirais kūdikystės laikotarpiais

    Pilypienė, Ingrida; Drazdienė, Nijolė; Dumalakienė, Irena; Vezbergienė, Nijolė; Bartkevičienė, Daiva; Šilkūnas, Mindaugas (2011)
    Intrauterine infection may induce fetal infectian and inflammation as weil as initiate the retal inflammatary response that is defined as retal inflammatary response syndrame (FIRS). FIRS could be the cause of heavy retal injuries and create health disarders for the preterms such as cerebral paralysis and chronic lung disease. Microoarganisms and their isolated substances induce fetal mononucleer cells to produce inflammatory markers, i.e. cytokines and chemokines possessing the ability to in...
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