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Open Access Repository of IISc Research Publications
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  • The polyglutamine motif is highly conserved at the Clock locus in various organisms and is not polymorphic in humans

    Circadian rhythms play a central role in diverse physiological phenomena and the recent years have witnessed the identification of a number of genes responsible for the maintenance of these rhythms. One of these is the Clock gene, which was first identified in mouse and subsequently in a large number of organisms, including humans. The human Clock gene has been proposed as a possible candidate for disorders affected by alterations of circadian rhythm, including bipolar disorder and schizophre...

    Selective Determination of Uric Acid in Presence of Ascorbic Acid and Dopamine at Neutral pH Using Exfoliated Graphite Electrodes

    Exfoliated graphite electrodes have been used to detect uric acid at neutral pHs, by following its oxidation. A linear range of 5-53 \mu M and a detection limit of 5 \mu M are observed at a pH of 7.0. Uric acid was found to be selectively adsorbed on exfoliated graphite surface in the presence of excess ascorbic acid. This leads to its selective determination in the presence of ascorbic acid. Simultaneous detection of uric acid, dopamine and ascorbic acid has also been demonstrated on exfolia...

    The True Origin of Agriculture: Credit Goes to the Ants

    Human agriculture which is believed to have originated some 10,000 years ago has rightly been considered the most important development in the history of our species. Virtually all the plants which we consume today are derived from cultivars that have been bred and modified by humans for thousands of years. There has also been extensive exchange of cultivated crops from one part of the globe to another. While consuming plants and their products, we tend to forget that the cultivation of coffe...

    Spectrally formulated wavelet finite element for wave propagation and impact force identification in connected 1-D waveguides

    In this paper, a novel wavelet based spectral finite element is developed for studying elastic wave propagation in 1-D connected waveguides. First the partial differential wave equation is converted to simultaneous ordinary differential equations (ODEs) using Daubechies wavelet approximation in time. These ODEs are then solved using finite element (FE) technique by deriving the exact interpolating function in the transformed domain. Spectral element captures the exact mass distribution and th...

    The change of complete symmetry of the crystals during the phase transitions in ferroelectrics and ferromagnetics

    The extension of the superposition principle of the symmetries (P. Curie principle of symmetry) for the case of complete symmetry is given. The enumeration of all crystallographical groups of complete symmetry is presented, the number of elements having complete symmetry for each class of the crystals being indicated. The change of complete symmetry of the crystals under the phase transitions is obtained by superimposing the elements of complete symmetry of polar or axial vectors on the one h...
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