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  • Der Einfluss von niedrig dosiertem Hydrocortison auf die Monozytenfunktion und HLA-DR Expression im septischen Schock

    The aim of this work was to study the influence of low dose hydrocortisone on monocyte´s function and HLA-DR expression on monocytes in patients suffering of septic shock. It was examined whether hydrocortisone acts antiinflammatory on monocytes in this setting. Methods: 84 patients with septic shock were enrolled between march 2002 and november 2005 in this placebo-controlled double-blind study. The study period was 28 days. Randomised patients were treated for 5 days with either 200mg...

    MR-Elastographie des menschlichen Gehirns

    The presented doctoral thesis evaluates Magnetic Resonance Elastography of the brain in terms of applicability, its reproducibility and its sensitivity towards structural alterations of the tissue. Experiments were performed on healthy subjects of various age and on patients suffering from Multiple Sclerosis. The mechanical excitation proved to be very reliable and not incrimatory to the volunteers. As less as 3.5 % of multifrequency experiments did not yield sufficient data for further a...

    Untersuchungen zum erforderlichen Field of View für die bildgebende 3D-Diagnostik in der Zahnmedizin

    Introduction: One of the most important characteristic of a CBCT unit in terms of radiation exposure and costs is the achievable imaging volume, the field of view (FoV). Although there are a number of recommendations for different FoV, these suggestions are not based on any scientific study and generally follow standards set by the industry. Either these FoV are too small to evaluate all important structures or too large and expose patients to unnecessary radiation. The aim of this s...

    Quantifizierung von oxidiertem Low-Density-Lipoprotein im Serum postmenopausaler Frauen

    Oxidized Low-Density-Lipoprotein (ox LDL) is of high importance for the mirco- and macrovascular modifications of atherosclerosis and is as well relevant for diagnosing atherogenic vascular modifications in diabetes mellitus, dyslipidemia and kidney disorder. This dissertation focused on testing a large proband group using for the first time the 1H-nuclear magnetic resonance spectroscopy (1H-NMR spectroscopy) to measure ox LDL. Methods 549 postmenopausal women completed a survey regard...

    Die Qualität der transthorakalen atemabhängigen Impedanz zur Erfassung von respiratorischen Ereignissen bei schlafbezogenen Atmungsstörungen im Vergleich zur stationären Polysomnographie

    Introduction: The goal of the study is to evaluate the diagnostic quality, with respect to sleep related breathing disorders (SRBS) of transthoracic impedance recording (TTIR) by comparing it to the gold standard method of in-hospital polysomnography (PSG). Method: We compared the performance of TTRI to the performance of in-hospital PSG in 60 patients who had suspect of sleep related breathing disorders. Characteristics of the group were typical for SRBS groups (49 ♂:11♀; age...
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