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Name
Repositório Científico do Centro Hospitalar do Porto
Type
Institutional Repository
Items
1400 Publications
Compatibility
OpenAIRE 3.0 (OA, funding)
OAI-PMH
http://repositorio.chporto.pt/oai/openaire
More information
Detailed data provider information (OpenDOAR)

 

  • Human immunodeficiency virus in medically assisted reproduction context: technical aspects and ethical considerations

    Pires, I. (2006)
    No início da epidemia da SIDA, devido ao mau prognóstico das pessoas infectadas com a doença, os casais com um parceiro infectado com VIH eram desencorajados de planear uma gravidez. Actualmente, a SIDA mantém-se como uma condição grave a nível mundial, e mesmo nos países industrializados onde estão disponíveis tratamentos inovadores e eficazes, a infecção por VIH continua a ser uma doença crónica com elevada morbilidade e mortalidade. No entanto, graças às...

    Urinary Biomarkers for Kidney Disease in ATTR Amyloidosis

    Rocha, A.; Bravo, F.; Beirão, I.; Vizcaíno, J.; Oliveira, J.; Lobato, L. (2014)
    Aim: The detection and prognosis of nephropathy in transthyretin amyloidosis depends on albuminuria and renal function. Knowing that urinary levels of alpha-1 microglobulin and beta-2 microglobulin reflect tubular dysfunction while urinary alpha-2 macroglobulin implies glomerular damage, we decide investigate the diagnostic value of these markers in the patients with transthyretin amyloidosis. Methods: Serum and urinary samples collected from 30 patients and 11 asymptomatic carriers were t...

    HUMAN BLOOD T AND NK CELL IN VITRO STIMULATION REVEALS A SIMILAR ACTIVATION PHENOTYPE THAT RESEMBLES EARLY ACTIVATION STAGES DURING ACUTE VIRUS INFECTION

    Moura, J.; Gonçalves, M:; Fonseca, S.; Santos, A.; Queirós, M.; Teixeira, M.; Lima, M. (2009)
    The complexity of T and NK-cell responses needs a great deal of control in the way these cells respond to stimulation. This is made by a precise regulation of gene expression leading to specific changes of membrane proteins, in order to acquire their full cytotoxic or immunological mediators secreting potential. The immunophenotypic changes occurring in-vivo on blood T and NK-cells in patients with acute and chronic infections have been previously characterized in detail, defining...

    Trombose tripla, simultânea, muito tardia de stents coronários

    Silva-Vieira, M.; Luz, A.; Anjo, D.; Antunes, N.; Santos, M.; Cyrne-Carvalho, H.; Torres, S. (2013)
    Abstract Coronary artery stent thrombosis is an uncommon but potentially catastrophic complication. The risk of very late stent thrombosis (VLST) raises important safety issues regarding the first generation of drug-eluting stents (DES). Although several complex mechanisms for VLST have been suggested and various predictors have been described, its pathophysiology is not completely understood and it is not known whether longer-term dual antiplatelet therapy reduces the risk. We present a r...

    Genes, children and paediatricians: Berardinelli-Seip syndrome

    Bandeira, A.; Cunha, S.; Álvares, S.; Martins, E. (2010)
    ABSTRACT A 13 years old boy presented an abnormal habitus since birth with generalized paucity of fat, muscular overdevelopment and hepatomegaly. Laboratory tests revealed increased triglycerides. Congenital generalised lipodystrophy was diagnosed.
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