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Name
eScholarship - University of California
Type
Institutional Repository
Items
121277 Publications
Compatibility
OpenAIRE Basic (DRIVER OA)
OAI-PMH
http://www.escholarship.org/uc/oai
More information
Detailed data provider information (OpenDOAR)

 

  • HIV-1 Tat-induced interleukin-10 from monocytes is subtype specific

    The human immunodeficiency virus type-1 (HIV-1) trans- acting regulatory protein (Tat) has been shown to induce interleukin-10 (IL-10) production in monocytes. IL-10, an anti-inflammatory cytokine, downregulates proinflammatory cytokines and suppresses the immune response, leading to a rapid progression from HIV-1 infection to AIDS. Nine subtypes of HIV-1 are responsible for the majority of infections worldwide. Recent studies demonstrate that different HIV-1 subtypes have biological differen...

    Single molecule studies of DNA packaging by bacteriophages

    The DNA packaging dynamics of bacteriophages [phi]29, [lambda], and T4 were studied at the single molecule level using a dual trap optical tweezers. Also, a method for producing long DNA molecules by PCR for optical tweezers studies of protein DNA interactions is presented and thoroughly characterized. This DNA preparation technique provided DNA samples for the [phi]29 and T4 studies. In the studies of [phi]29, the role of charge was investigated by varying the ionic conditions of the packagi...

    Staging History in Modern and Contemporary Spanish Drama

    This dissertation explores the manifestations, uses and appropriations of history in key Spanish plays from the 1950s to the present. The relationship between the stage and history casts new light on Spain's most critical phases in recent history. The authors studied were and are conscious of making history under the dictatorship, during the Transition and at the dawn of the 21st century. As instruments of civic action, their plays perform that awareness and invite spectators to recognize the...
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