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eScholarship - University of California
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  • Active Set Methods for Isotone Optimization

    Isotone optimization is formulated as a convex programming problem with simple linear constraints. A R implementation of a particular active set strategy is discussed, and applied to various isotone optimization problems important in statistics. The implementation is user-extendable, and handles a great many convex loss functions and partial orders.

    Conducting an Interactive Survey of Household Weekly Activities via Internet: Preliminary Results from a Pilot Study

    The primary goal of activity-based models is a fundamental examination of the behavioral process that results in revealed travel behavior. To reveal this process, a new computer program, REACT!1, has been developed to collect data for a study of the determinants of travel and activity behavior in households. This data is inherently dynamic, since respondents record planned activity schedules and then update these schedules, on a daily basis, fully defined in time and space. The resultant data...

    In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

    The low number of CD4+ CD25+ regulatory T cells (Tregs), their anergic phenotype, and diverse antigen specificity present major challenges to harnessing this potent tolerogenic population to treat autoimmunity and transplant rejection. In this study, we describe a robust method to expand antigen-specific Tregs from autoimmune-prone nonobese diabetic mice. Purified CD4+ CD25+ Tregs were expanded up to 200-fold in less than 2 wk in vitro using a combination of anti-CD3, anti-CD28, and interleuk...

    The importance of prey aggregations to the distribution of Brunnich's guillemots in Storfjorden, Svalbard

    We studied the influence of the distribution of prey and hydrographic fronts on the spatial distribution of foraging Brunnich's guillemots (Uria lomvia) in Storfjorden, southeastern Svalbard in late July 1992. Two large breeding colonies, comprising a total of 540,000 individuals, were located adjacent to the study area, and large numbers of Brunnich's gullemots from these colonies foraged within the area, as well as to the south, outside of Storfjorden. Within the study area, most guillemots...

    Surveying for Environmental Health Justice: Community Organizing Applications of Community-Based Participatory Research

    © 2016, Mary Ann Liebert, Inc.Although the benefits of community-based participatory research (CBPR) for community and university partners have been well documented, these have mostly focused on disseminating research findings. However, how CBPR can function as a useful community organizing tool remains understudied. We present the CBPR process of an environmental health survey conducted by a team of community organizers and academic researchers in Richmond, CA, to describe how survey researc...
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