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eScholarship - University of California
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  • Cellular Mechanotransduction via Microfabricated Post Arrays

    Substrate-based biophysical cues, which interact with cells through mechanotransductive pathways, influence many biological processes and cellular behaviors. By leveraging microfabrication techniques, this work aims to build biophysical stimuli into cellular substrates through discrete microtopographic features to study cellular responses. Here, uniform and gradient arrays of circular microposts have been geometrically tuned to change the apparent rigidity of a substrate and the placement of ...

    Processes Affecting Agricultural Drainwater Quality and Organic Carbon Loads in California's Sacramento–San Joaquin Delta

    From 2000 to 2003 we quantified drain flow, drain-and ground-water chemistry and hydrogeologic conditions on Twitchell Island in the Sacramento-San Joaquin Delta. The primary objective was to quantify processes affecting organic carbon concentrations and loads in agricultural drainage water. We collected physical and chemical data in southern and northern areas: TN and TS, respectively. Corn grew in both areas during the spring and summer. The peat soils in the TN area are more decomposed tha...

    Here or there? Consumer reactions to corporate social responsibility initiatives: Egocentric tendencies and their moderators

    This research examines how consumers react to corporate social responsibility (CSR) programs that vary in geographic focus. Three experiments compare consumers' patronage of a company in response to local and distant CSR initiatives. The extant egocentrism literature suggests that a CSR activity focused locally, and thus, with greater personal relevance, should increase patronage of the company responsible for the CSR activity. Indeed, this egocentric bias, exhibited in the form of increased ...

    Engineering Nanoscale Multiferroic Composites for Memory Applications with Atomic Layer Deposition of Pb(ZrxTi1-x)O3 Thin Films

    This work focuses on the development of atomic layer deposition (ALD) for lead zirconate titanate, Pb(ZrxTi1-x)O3 (PZT). Leveraging the surface-reaction controlled process based on alternating self-limiting surface reactions, PZT can be synthesized not only with elemental precision to realize the desired composition (Zr/Ti = 52/48) but also with outstanding conformality. The latter enables the integration of PZT with a ferromagnetic phase to realize multiferroism (MF) and magnetoelectric (ME...

    Weight Loss Associated with Cholinesterase Inhibitors in Individuals with Dementia in a National Healthcare System

    © 2015, Copyright the Authors Journal compilation © 2015, The American Geriatrics Society. Objectives To determine whether initiation of cholinesterase inhibitors is associated with significant weight loss in a real-word clinical setting. Design Retrospective cohort study from 2007 to 2010 comparing weight loss in individuals with dementia newly prescribed cholinesterase inhibitors and those newly prescribed other chronic medications. Setting National Veterans Affairs data. Participants Indiv...
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