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  • Electron spins in single and double quantum dots : transport, correlations and decoherence

    This thesis is devoted to the study of electron spins in quantum dots. In recent years, the quantum dots have evolved towards smaller sizes and a better control over the number of electrons on a dot. Comparing to a decade ago, when the quantum dots were containing hundreds of electrons and behaving unpredictably under small changes of their electrostatic or magnetic environment, today, the state-of-the-art quantum dots resemble rather atoms (with well-organized electronic shell...

    In vitro characterization of psychoactive substances at rat, mouse, and human trace amine-associated receptor 1

    Trace amine-associated receptor 1 (TAAR1) has been implicated in the behavioral effects of amphetamine-type stimulant drugs in rodents. TAAR1 has also been suggested as a target for novel medications to treat psychostimulant addiction. We previously reported that binding affinities at TAAR1 can differ between structural analogs of psychostimulants, and species differences have been observed. In this study, we complement our previous findings with additional substances and the determination of...

    No plastic responses to experimental manipulation of sperm competition in a free-living flatworm

    In the absence of sperm competition evolutionary theory predicts low mating rates and low ejaculate expenditure per mating, and sex allocation theory for simultaneous hermaphrodites predicts a strongly female-biased sex allocation. In the presence of sperm competition a shift towards a more male-biased sex allocation and a higher ejaculate expenditure are predicted. The free-living flatworm Macrostomum lignano has been shown to respond plastically in mating rate, testis size, and sperm transf...

    Examination of alternative splice code of neurexins for synaptic specification

    The brain is composed of a large number of cells types that assemble together into highly specific circuits. Precise connectivity is crucial to ensure proper brain functions and requires mechanisms that generate molecular diversity to encode certain aspects of neuronal wiring. One possible mechanism to generate molecular diversity is alternative splicing. For example through alternative splicing Neurexin (Nrxn1-2-3) genes have the potential to give rise to more than 12’000 protein isoforms (T...
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