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Name
Universidade do Minho: RepositoriUM
Type
Institutional Repository
Items
28927 Publications
Compatibility
OpenAIRE 3.0 (OA, funding)
OAI-PMH
http://repositorium.sdum.uminho.pt/oai/driver
More information
Detailed data provider information (OpenDOAR)

 

  • Synthesis of fluorescent alanines by a rhodium catalysed conjugate addition of arylboronic acids to dehydroalanine derivatives

    Several arylalanine derivatives containing fluorescent groups were prepared in good yields using a rhodium catalysed conjugate addition of arylboronic acids to N,N-diprotected and N-monoprotected dehydroalanines. The best conditions for these reactions require the use of an excess of aryl boronic acid (4 equiv.), [Rh(COD)2]BF4 as catalyst and CsF as base in dioxane:H2O (10:1) at 110 ºC. These conditions were also applied to several dipeptides with dehydroalanine residues. The photophysical pr...

    Ecology and environment, an urban scale comparative study between contemporary and vernacular city of Nablus

    The harmony between environment and buildings is the strongest point of vernacular architecture. In this context, the Mediterranean vernacular architecture is harmonized with its local context, including culture and traditions. In addition, it respects environmental and climatic factors, construction materials and morphology. In the past, people in Palestine built their houses according to their possibilities, needs, available materials, topography, and culture. Without any control from the g...

    IL-27-regulated signalling pathways in Angiogenesis-possible role of MAPKinases

    Dissertação de mestrado em Genética Molecular Angiogénese é o crescimento de vasos sanguíneos a partir de vasos pré-existentes. Sabe-se que é um processo envolvido em várias doenças inflamatórias, sobretudo devido a um desequilíbrio entre factores pro-­ e anti-angiogénicos no tecido inflamado. IL-­27 é uma citocina produzida por células apresentadoras de antigénios, com propriedades pro- e anti-inflamatórias e potencial anti-angiogénico. Os sinalizadores de tradução e ativação de transcriç...

    Ecriture et mémoire : écrire après la Shoah

    Tese de Doutoramento em Ciências da Literatura - Ramo do Conhecimento de Literatura Francesa Le vaste domaine de la littérature des écrivains de la «deuxieme génération» de I'Holocauste est intimement marqué par la recherche des moyens d'expression de l'absence et du manque de tout ce qui a disparu. Robelt Bober, Raymond Federman, Patrick Modiano et Georges Perec engagent leur pratique littéraire dans un travail profond sur les modes d'écriture qui semblent être le seul moyen de parvenir à...

    Spatial-temporal control of the early stages of somitogenesis in the chick embryo

    Tese de Doutoramento em Ciências da Saúde A segmentação é o processo que conduz à formação dos sómitos, estruturas embrionárias metaméricas que se formam na parte mais rostral da mesoderme presomítica (MPS) e que estão na base da segmentação do corpo dos vertebrados. Sabese actualmente que o processo de segmentação é controlado por um relógio molecular que opera ao nível das células da MPS e que se manifesta pela transcrição cíclica de vários genes, cujo tempo de ciclo corresponde...
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