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Name
Repositório Científico do Instituto Nacional de Saúde
Type
Institutional Repository
Items
2678 Publications
Compatibility
OpenAIRE 3.0 (OA, funding)
OAI-PMH
http://repositorio.insa.pt/oai/openaire
More information
Detailed data provider information (OpenDOAR)

 

  • Polyclonal KPC-3-producing Enterobacteriaceae in Portugal

    Manageiro, Vera; Ferreira, Eugénia; Louro, Deolinda; Caniça, Manuela; Antimicrobial Resistance Surveillance Program in Portugal (ARSIP) (2012)
    Water has been recognized as a reservoir for antibiotic resistance genes (ARG), where the presence of mobile genetic elements, including plasmids, favors their dissemination. It is noteworthy that nonpathogenic environmental organisms, where plasmids encoding multiple ARG are prevalent, can provide resistance to most classes of antimicrobials including beta-lactams, aminoglycosides, chloramphenicol, trimethoprim, streptomycin, fosfomycin, quinolones, among others. The main goal of...

    Glucose-6-phosphate dehydrogenase deficiency in Portugal: biochemical and mutational profiles, heterogeneity, and haplotype association

    Rodrigues, M.O.; Freire, A.P.; Martins, G.; Pereira, J.; Martins, M.C.; Monteiro, C. (2002)
    Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common human enzymopathy. This deficiency in erythrocytes has a prevalence of 0.51 +/- 0.109 in the Caucasoid male population of Portugal. The frequency for deficiency-conferring genes is 0.39% in the Portuguese population. In the herein study populations males from areas of Portugal presenting with the highest prevalence of G6PD deficiency (Castelo Branco, Setúbal, Faro, and Lisbon) as well as similar subjects located in the bor...

    Fatores genéticos moduladores dos níveis elevados de hemoglobina fetal na Anemia de Células Falciformes

    Almeida, Teresa; Mateus, Íris; Braga, Lígia; Freitas, Orquídia; Kjollerstrom, Paula; Faustino, Paula (2014)
    A Drepanocitose ou Anemia das Células Falciformes (ACF) é uma anemia hereditária de transmissão autossómica recessiva caraterizada pela presença de hemoglobina S (HbS) devido à homozigotia para a mutação A>T no codão 6 do gene da beta-globina (HBB:c.20A>T). Embora se trate de uma doença monogénica, o seu fenótipo clínico é bastante heterogéneo. Este fato deve-se à influência modificadora tanto de fatores ambientais como de fatores genéticos. De entre estes últimos, salienta-se o nível elevado...

    Exposição de crianças a múltiplas micotoxinas através do consumo de alimentos: uma abordagem holística à avaliação de risco

    Assunção, Ricardo (2017)
    Projects: FCT | PTDC/DTP-FTO/0417/2012 (124803)
    Tese de doutoramento em Ciências Veterinárias apresentada ao Departamento de Medicina Veterinária da Universidade de Évora, 2017 Co-oientadoras: Paula Cristina da C. O. Soromenho de Alvito e lsa Maria da Cruz Reis Vasco - Departamento de Alimentação e Nutruição do INSA. The research work was mainly developed at the Food and Nutrition Department of the National Institute of Health Dr. Ricardo Jorge, Lisbon, Portugal (INSA) and also at the Department of Chemistry, Biotechnology and ...

    Carotenoides em frutos e produtos hortícolas tradicionais portugueses

    Dias, M. Graça; Oliveira, Luísa (2015)
    Objetivos: O principal objetivo deste estudo foi conduzir uma investigação sobre o potencial valor alimentar de frutos e produtos hortícolas tradicionais portugueses, focada nos carotenoides, -caroteno, -caroteno, -criptoxantina, licopeno, luteína e zeaxantina, sobre os quais a Tabela Portuguesa de Composição de Alimentos é omissa. Pretendeu-se assim contribuir para colmatar a escassez de dados analíticos da composição de alimentos produzidos em Portugal, essenciais em...
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