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Name
Padua@research
Type
Institutional Repository
Items
2154 Publications
Compatibility
OpenAIRE 2.0+ (DRIVER OA, EC funding)
OAI-PMH
http://paduaresearch.cab.unipd.it/cgi/oai2
More information
Detailed data provider information (OpenDOAR)

 

  • Formation and function of neural circuitry in the olfactory bulb of mice with reduced afferent spontaneous activity

    Redolfi, Nelly (2014)
    In the sensory systems, peripheral neurons project axons in specific loci of the brain. The spatial segregation of the sensory afferents provides topographic maps that define the quality and the location of complex sensory stimuli. Electrical activity plays a critical role in the formation of specific synaptic contacts among neurons, although the type of activity required remains a matter of significant debate. In particular the role of spontaneous activity in the formation of the topographic...

    Behavioural and electrophysiological indices of executive functions in ageing and in Parkinson's disease

    Di Rosa, Elisa (2014)
    Healthy ageing and Parkinson's disease (PD) are both characterized by different changes in the prefrontal cortex and in dopaminergic functionality. Working memory and feedback processing have been related to the dopaminergic activity in the prefrontal cortex (Hammerer & Eppinger, 2012; Backman et al., 2010-2008; Backman & Farde, 2005). The aim of the three studies presented in this thesis was to examine if, and how, these two executive functions change in ageing and in Parkinson's disease pat...

    IL DIRITTO D'ACCESSO AL TERRITORIO FRA TUTELA DELL'INDIVIDUO MIGRANTE E SOVRANITÀ DELLO STATO: ANALISI DI UN CONFLITTO

    Carrara, Lucia (2016)
    The decision of a State regarding the stay of an individual who is not a citizen in its territory is subject to norms of International Law; nevertheless, those norms can have different recipients and ratio, and they may often end up being in mutual competition, so that one’s satisfaction means the other’s partial or total detriment. On one hand, States are allowed by International Law to freely determine their own population; on the other hand, migrants are beneficiaries of rights whose prote...

    Applicazione comparativa di metodiche di sequenziamento di nuova generazione (NGS) nella diagnosi di Neurofibromatosi di tipo 1

    Rossi, Silvia (2017)
    Neurofibromatosis type 1 is one of the most frequent autosomal dominant diseases affecting 1 in 3000 individual worldwide. This disorder is caused by heterozygous inactivating mutations of NF1, a large gene that encodes neurofibromin, a negative regulator of the RAS pathway. The mutation rate at the NF1 locus is one of the highest reported in any human disorder; this observation is reflected in the finding that almost 50% of all NF1 patients exhibit a de novo NF1 mutation. More than 1900 diff...

    A harmonized approach towards immuno-monitoring of myeloid-derived suppressor cells for prediction of clinical outcomes in melanoma patients treated with ipilimumab

    Damuzzo, Vera (2015)
    Ipilimumab is a monoclonal antibody against cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) that belongs to a new class of immunotherapeutic drugs called immune checkpoint inhibitors (ICI) which prevent the feedback inhibition of activated T cells and hold great promise to treat cancer. Indeed, it has been demonstrated that ipilimumab increases overall survival (OS) of metastatic melanoma patients, but a durable 5-year survival benefit is observed in a proportion of patients ranging from...
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