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UEF eRepository
Institutional Repository
856 Publications
OpenAIRE 2.0+ (DRIVER OA, EC funding)
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  • No Association Between Proton Pump Inhibitor Use and Risk of Alzheimer's Disease

    Taipale H; Tolppanen AM; Tiihonen M; Tanskanen A; Tiihonen J; Hartikainen S (2017)
    Objectives: The objective of the study was to investigate whether proton pump inhibitor (PPI) use is associated with an increased risk of clinically verified Alzheimer’s disease (AD). Methods: A Finnish nationwide nested case–control study MEDALZ includes all community-dwelling individuals with newly diagnosed AD during 2005–2011 (N=70,718), and up to four age-, sex-, and region of residence-matched comparison individuals for each case (N=282,858). Data were extracted from Finnish...

    In vitro toxicological effects of zinc containing nanoparticles with different physico-chemical properties

    Uski O; Torvela T; Sippula O; Karhunen T; Koponen H; Peräniemi S; Jalava P; Happo M; Jokiniemi J; Hirvonen M-R; Lähde A (2017)
    Nanomaterials (NM) exhibit novel physicochemical properties that determine their interaction with biological substrates and processes. Recent nano-technological advances are leading to wide usage of metallic nanoparticles (NPs) in various fields. However, the increasing use of NPs has led to their release into environment and the toxicity of NPs on human health has become a concern. Moreover, there are inadvertently generated metallic NPs which are formed during various human activities (e.g....

    A mobile context-aware medical training system for the reduction of pathogen transmission

    Tortorella Richard AW; Kinshuk (2017)
    Even with the adoption of modern technology within the medical system, the spread of deadly pathogens remains a silent, yet deadly killer. Indeed, e-health, and in particular m-health is at the forefront of the computing portion of modern medical care. It follows the ubiquity of mobile computing devices that has become synonymous with modern life. Although the focus of m-health is patient based, this paper attempts to provide a focus on the healthcare service provider in an attempt to reduce ...

    I-SLATE: designing a culturally relevant framework for authentic learning

    Loewen John; Kinshuk; Suhonen Jarkko; Chen Nian-Shing (2017)
    Many Indigenous learners worldwide find the learning materials presented in current educational settings culturally irrelevant. A lack of relevant learning materials within formal education settings subscribing to Western Euro-centric curriculum standards is a key factor. Learning materials provided through modelling, practice, and apprenticeship, are desired. With the literature identifying the lack of a formal curriculum design process, a framework is presented for standardized creation of ...

    Genomic Reconstruction of the History of Native Sheep Reveals the Peopling Patterns of Nomads and the Expansion of Early Pastoralism in East Asia

    Zhao Yong-Xin; Yang Ji; Lv Feng-Hua; Hu Xiao-Ju; Xie Xing-Long; Zhang Min; Li Wen-Rong; Liu Ming-Jun; Wang Yu-Tao; Li Jin-Quan; Liu Yong-Gang; Ren Yan-Ling; Wang Feng; Eer Hehua; Kantanen Juha;... (2017)
    China has a rich resource of native sheep (Ovis aries) breeds associated with historical movements of several nomadic societies. However, the history of sheep and the associated nomadic societies in ancient China remains poorly understood. Here, we studied the genomic diversity of Chinese sheep using genome-wide SNPs, mitochondrial and Y-chromosomal variations in > 1,000 modern samples. Population genomic analyses combined with archeological records and historical ethnic demographics data rev...
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