Global dynamics of a piece-wise epidemic model with switching vaccination strategy
Wang, Aili; Xiao, Yanni; Cheke, Robert A.(2014)
American Institute of Mathematical Sciences
A piece-wise epidemic model of a switching vaccination program, implemented once the number of people exposed to a disease-causing virus reaches a critical level, is proposed. In addition, variation or uncertainties in interventions are examined with a perturbed system version of the model. We also analyzed the global dynamic behaviors of both the original piece-wise system and the perturbed version theoretically, using generalized Jacobian theory, Lyapunov constants for a non-smooth vector field and a generalization of Dulac's criterion. The main results show that, as the critical value varies, there are three possibilities for stabilization of the piece-wise system: (i) at the disease-free equilibrium; (ii) at the endemic states for the two subsystems or (iii) at a generalized equilibrium which is a novel global attractor for non-smooth systems. The perturbed system exhibits new global attractors including a pseudo-focus of parabolic-parabolic (PP) type, a pseudo-equilibrium and a crossing cycle surrounding a sliding mode region. Our findings demonstrate that an infectious disease can be eradicated either by increasing the vaccination rate or by stabilizing the number of infected individuals at a previously given level, conditional upon a suitable critical level and the parameter values.
Greenwich Academic Literature Archive (http://gala.gre.ac.uk/12198/1/12198_CHEKE_DCDS_%282014%29_%28AAM%29.pdf)