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Kyriacou, P. A.

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P. A.
  • Direct pulse oximetry within the esophagus, on the surface of abdominal viscera, and on free flaps

    Pulse oximetry is a noninvasive photometric technique that provides information about arterial blood oxygen saturation (SpO2) and heart rate and has widespread clinical applications. This is accomplished via peripheral pulse oximetry probes mainly attached to the finger, toe, or earlobe. The direct application of pulse oximetry to an organ, such as the esophagus, liver, bowel, stomach or free flap, might provide an indication of how well perfused an organ or a free flap is. Also, the placemen...

    Estimation of Venous oxygenation saturation using the finger Photoplethysmograph (PPG) waveform

    In this study, finger photoplethysmograph data obtained from twelve patients undergoing cardiothoracic surgery were analyzed in order to estimate the venous saturation utilizing the modulations created by the positive pressure ventilation in the AC Photoplethysmograph (PPG) signals. The PPG signals were analyzed in the time-domain using a conventional pulse oximetry algorithm to produce estimations of arterial oxygen saturation. The instantaneous arterial and venous saturations were estimated...

    Pulse oximetry in the oesophagus

    Pulse oximetry has been one of the most significant technological advances in clinical monitoring in the last two decades. Pulse oximetry is a non-invasive photometric technique that provides information about the arterial blood oxygen saturation (SpO(2)) and heart rate, and has widespread clinical applications. When peripheral perfusion is poor, as in states of hypovolaemia, hypothermia and vasoconstriction, oxygenation readings become unreliable or cease. The problem arises because conventi...

    Development and in vitro evaluation of an artificial spinal disc loading cell

    One of the common diseases for chronic low back pain is Disc Degeneration Disease (DDD). In this disease, spinal intervertebral disc loses its ability to safely handle the mechanical stresses. The knowledge of the in-vivo loading on the spinal disk is of great importance in the understanding of low back pain. In this study a loading cell has been developed utilizing an artificial spinal disc which was loaded with strain gauges and piezoresistive sensors in an effort to investigate the behavio...

    Temperature sensor technology

    Human body temperature is of vital importance to the well being of the person and therefore it is routinely monitored to indicate the state of the person’s health. Despite the fact that temperature measurement in humans seems so simple, a wide variety of devices are available to record a temperature from skin, oral or rectal mucosa or the tympanic membrane. The choice of clinical thermometers for health professionals and parents has never been so complicated. \ud \ud This chapter makes an att...

    Improved measurement technique for the characterisation of phase change materials using the T-history method

    Recently the interest in Phase Change Materials (PCMs) has grown significantly amongst researchers [1-9]. Namely, these materials, due to their ability to store large amounts of thermal energy in relatively small temperature intervals, can be effectively used for various thermal energy storage (TES) applications. Nevertheless, accurate knowledge of the thermal properties of PCMs is a prerequisite before design processes and real time deployments of any TES applications. \ud \ud The T-history ...

    Photoplethysmographic sensors for perfusion measurements in spinal cord tissue

    Sensors for recording photoplethysmographic signals from the nervous tissue of the spinal cord are described. The purpose of these sensors is to establish whether perfusion is compromised in various states of injury which occur in certain animal models of spinal cord injury, for example compression injury. Various measures of perfusion are applicable such as the amplitude of the photoplethysmograph signal and the oxygen saturation, measured using a dual wavelength configuration. Signals are u...

    Theory of Dynamic Pulsatile Spectroscopy for photoplethysmographic signals analysis

    Photoplethysmography (PPG) is a technique that uses light to non-invasively obtain a volumetric measurement of an organ with each cardiac cycle. Pulse Oximetry (PO) is an empirical technique which allows the arterial blood oxygen saturation (SpO2) evaluation from the PPG signals. There have been many reports in the literature suggesting that other arterial blood chemical components can be evaluated from the PPG signals. Most attempts to perform such evaluation on empirical bases have failed, ...

    Beer-Lambert law along non-linear mean light pathways for the rational analysis of Photoplethysmography

    Photoplethysmography (PPG) is a technique that uses light to noninvasively obtain a volumetric measurement of an organ with each cardiac cycle. A PPG-based system emits monochromatic light through the skin and measures the fraction of the light power which is transmitted through a vascular tissue and detected by a photodetector. Part of thereby transmitted light power is modulated by the vascular tissue volume changes due to the blood circulation induced by the heart beating. This modulated l...

    Photoplethysmographic signals and blood oxygen saturation values during artificial hypothermia in healthy volunteers

    Pulse oximetry utilizes the technique of photoplethysmography to estimate arterial oxygen saturation (SpO2) values. During hypothermia, the amplitude of the photoplethysmograph (PPG) is compromised which can lead to inaccurate estimation of SpO2. A new mutlimode PPG/pulse oximeter sensor was developed to investigate the behaviour of PPGs during conditions of induced hypothermia (hand immersed in an ice bath). PPG measurements from 20 volunteers were conducted and SpO2 values were estimated at...
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