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Fedorov, S. V.

Last name
Fedorov
First name
S. V.
Country
-
  • Effect of Ivabradine and -3 Polyunsaturated Fatty Acids on Clinical Manifestations of Heart Failure of Ischemic Genesis

    Heart failure (HF) is a major public health issue with a current prevalence of over 5.8 million in the USA and over 23 million worldwide. Ischemic heart disease is known to be the most important risk factor for HF. Ivabradine is a new therapeutic agent designed to reduce heart rate at rest and during exercise by selective inhibition of a novel receptor (If channel) located on the pacemaker-cell membrane within the sinoatrial node. As such, ivabradine joins a list of rate-limiting medications ...

    THE EFFECT OF IVABRADINE AND OMEGA-3 POLYUNSATURATED FATTY ACIDS ON INNATE IMMUNITY IN PATIENTS WITH HEART FAILURE

    Heart failure (HF) is a major public health issue with a current prevalence of over 5.8 million in the USA and over 23 million worldwide. Ischemic heart disease is known to be the most important risk factor for HF. Ivabradine is a new therapeutic agent designed to reduce heart rate at rest and during exercise by selective inhibition of a novel receptor (If channel) located on the pacemaker-cell membrane within the sinoatrial node.  As such, ivabradine joins a list of rate-limiting medications...

    Energy Criterion of Oil Film Failure during Friction

    The concepts developed by the thermodynamic theory of solid body strength and fracture are used to examine the conditions of lubricant film failure. We obtain a quantitative criterion that defines the lubricant film "defectness" - the critical value (constant for a given mineral oil) of the internal (thermal) energy density in the volume of the lubricant film. We propose analytic relations for evaluating scuffing in friction with lubrication and verify them experimentally on a full-scale stan...

    Вплив івабрадину та ω-3 поліненасичених жирних кислот на рівні цитокінів у хворих із серцевою недостатністю ішемічного ґенезу

    The aim of our study was to evaluate of the possible effect of ivabradine and ω-3 polyunsaturated fatty acids on the levels of pro- and anti-inflammatory cytokines in patients with ischemic heart failure. 357 patients with ischemic HF and the sinus rhythm were observed. In accordance to treatment all patients were divided into four groups. The levels of interleukin 1β (IL-1β), interleukin 6 (IL-6), and interleukin 10 (IL-10 ) in the serum were determined using commercial ELISA kits according ...

    Energy Balance of Friction and Friction Coefficient in Energetical Interpretation

    Sliding friction energy model is proposed. In this model, generalized mechanism of transformation and dissipation of energy under friction the model of elastic-plastic deformation and fracture contact volumes is considered. Energy model of the process of plastic deformation and destruction of solid bodies is based on the concept of ergodynamic of deformable bodies. Equations of energy balance of friction within the structural and energetic interpretation of deformation are proposed. The energ...

    The plasma levels of fibronectin in patients with ischemic heart failure

    The main element of heart failure progression is extracellular matrix condition, where the fibronectin is an important component. Aim.To investigate the plasma levels of fibronectinin patients with ischemic heart failure. Methods and results. The identification of the plasma levels of fibronectin’s concentration was made by ELISA method. Conclusion. The fibronectin plasma levels are higher in patients with II-III HF (NYHA) and at presence of atrial fibrillation. The main important...

    Вплив івабрадину та ω-3 поліненасичених жирних кислот на рівні плазмового фібронектину у хворих із серцевою недостатністю

    Серцева недостатність (СН) – кінцева стадія більшості захворювань серця та головна причина захворюваності і смертності. На лікування СН витрачається понад 2% національних видатків на охорону здоров’я. Фібронектин (Фн) відіграє ключову роль у процесах тканинно-специфічного морфогенезу та диференціації клітин під час ембріогенезу; стимулює фібробласти та різноманітні ростові фактори під час загоєння ран та репарації тканин. Досліджено ймовірний вплив івабрадину та препарату ω-3 поліненасичених ...

    Кариологические показатели моноцитов/макрофагов у больных хронической сердечной недостаточностью

    В последнее время активно изучается роль генетических факторов в формировании хронической сердечной недостаточности. С целью изучения цитогенетического статуса больных сердечной недостаточностью ишемического генеза обследовали 24 больных и 12 практически здоровых людей (группа контроля), у которых проводили кариологический анализ моноцитов/макрофагов. При сердечной недостаточности чаще отмечали наличие междуядерных мостиков, перинуклеарной вакуолизации, вакуолизации и конденсации ядерного хро...

    TECHNICAL AND ECONOMICAL ANALYSIS OF THE DEVELOPMENT OF NORTH-SOSVINSK BROWN-COAL FINDINGS

    In 2006, the company of "Uralgiproshaht" produced a work "based on the investing of the development and acquiring North-Sosvinsk coal findings". The article brings forth the results of technical and economical findings based on the open development of Liulinskiy, Otorinskiy, and Toliinskiy brown-coal findings.

    About the calculation of reduced total thermal resistance of walling

    Walling of modern buildings are characterized by high thermotechnical heterogeneity. It causes difficulties in the calculation of their thermal resistance. The universal method for estimation of heat-protection properties is the calculation of thermal fields with using of appropriate software. In the article complicated elements of this calculation such as the choice of rated operating conditions, level of detal of its decomposition, calculation results handling, features of calculation of p...
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