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Møller, H

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  • Cancer occurrence in a cohort of patients surgically treated for peptic ulcer.

    A cohort of 4107 patients treated surgically for peptic ulcer between 1955 and 1960 was followed up to determine the incidence of cancer by record linkage to the Danish Cancer Registry. A total of 930 cases of cancer were observed during 76,634 person-years. Relative risks of cancer were computed by comparison with the recorded cancer incidence in the Danish population. During the first five years after surgery the relative risk of gastric cancer was slightly increased (RR = 1.43), but 5-15 y...

    A person-time analysis of hospital activity among cancer survivors in England

    Background: There are around 2 million cancer survivors in the UK. This study describes the inpatient and day case hospital activity among the population of cancer survivors in England. This is one measure of the burden of cancer on the individual and the health service. Methods: The national cancer registry data set for England (1990?2006) is linked to the NHS Hospital Episode Statistics (HES) database. Cohorts of survivors were defined as those people recorded in the cancer registry data wi...

    The occurrence of invasive cancers following a diagnosis of breast carcinoma in situ.

    Approximately 1 in every 600 women attending breast-screening programmes in the United Kingdom is diagnosed with breast carcinoma in situ (BCIS). However, there is little information on the occurrence of subsequent cancers (other than second breast cancers) in these women. We investigated the occurrence of invasive cancers in 12,836 women diagnosed with BCIS in southeast England between 1971 and 2003, using data from the Thames Cancer Registry. A greater than expected number of subsequent can...

    Breast cancer screening uptake among women from different ethnic groups in London: a population-based cohort study

    OBJECTIVE To use newly available self-assigned ethnicity information to investigate variation in breast cancer screening uptake for women from the 16 specific ethnic groups within the broad Asian, Black and White groups that previous studies report. SETTING National cancer screening programme services within London. PARTICIPANTS 655 516 female residents aged 50-69, invited for screening between March 2006 and December 2009. Ethnicity information was available for 475 478 (72.5%). White Britis...

    Use of cimetidine and other peptic ulcer drugs in Denmark 1977-1990 with analysis of the risk of gastric cancer among cimetidine users.

    The prevalence of use of peptic ulcer drugs in the Danish population is described at two points in time using registrations of applications for reimbursement. In 1977-81, the prevalence of use of cimetidine was 0.4% in men and 0.2% in women. In 1989-90, the prevalence of use of peptic ulcer drugs was 1.3% in men and 1.2% in women. The increase in prevalence was apparent in all age groups, but most pronounced at relatively old age. The median age of users increased from 55 years in 1977-81 to ...

    A comprehensive assessment of the impact of errors in the cancer registration process on 1- and 5-year relative survival estimates

    Background:When making international comparisons of cancer survival, it is essential reported differences are real effects and not an artefact of potential errors in cancer registration.Methods:We use simulation methods to assess the impact of various cancer registration errors on commonly reported outcomes of cancer survival (1-, and 5-year relative survival estimates). We draw two samples of patients diagnosed with cancer from one population and introduce potential registration errors in on...

    Projections of cancer prevalence in the United Kingdom, 2010?2040

    Background: There are currently two million cancer survivors in the United Kingdom, and in recent years this number has grown by 3% per annum. The aim of this paper is to provide long-term projections of cancer prevalence in the United Kingdom. Methods: National cancer registry data for England were used to estimate cancer prevalence in the United Kingdom in 2009. Using a model of prevalence as a function of incidence, survival and population demographics, projections were made to 2040. Diffe...

    Risk of testicular cancer after vasectomy: cohort study of over 73,000 men.

    OBJECTIVE--To confirm or refute reports that vasectomy may increase the risk of cancers of the testis and prostate. DESIGN--Computerised record linkage study of cohort of men with vasectomy and comparison of cancer rates with those in the whole Danish population; manual check of all records of patients with testicular and prostate cancer diagnosed within the first year of follow up. SETTING--Denmark 1977-89. SUBJECTS--Cohort of 73,917 men identified in hospital discharge and pathology registe...

    Trends in incidence of anal cancer in Denmark.

    OBJECTIVE--To study long term trends in incidence of anal cancer in a well monitored, unselected population. DESIGN--Descriptive epidemiological study based on data from the Danish Cancer Registry. SETTING--Denmark, 1943-87. MAIN OUTCOME MEASURES--Time related changes in anal cancer incidence according to sex, age, birth cohort, urban or rural residence, and marital status. RESULTS--The incidence of anal cancer remained fairly constant in the period 1943-57 and was similar for men and women, ...
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