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The development and evaluation of a new therapy for the prevention and treatment of bacterial infections in hospitals

Title
The development and evaluation of a new therapy for the prevention and treatment of bacterial infections in hospitals
Funding
ARC | Linkage Projects
Contract (GA) number
LP110200752
Start Date
2011/01/01
End Date
2014/12/31
Open Access mandate
no
Organizations
-
More information
http://purl.org/au-research/grants/arc/LP110200752

 

  • Bovine antibodies targeting primary and recurrent Clostridium difficile disease are a potent antibiotic alternative

    Hutton, Melanie L.; Cunningham, Bliss A.; Mackin, Kate E.; Lyon, Shelley A.; James, Meagan L.; Rood, Julian I.; Lyras, Dena (2017)
    Projects: ARC | The development and evaluation of a new therapy for the prevention and treatment of bacterial infections in hospitals (LP110200752)
    The increased incidence of antibiotic resistant ‘superbugs’ has amplified the use of broad spectrum antibiotics worldwide. An unintended consequence of antimicrobial treatment is disruption of the gastrointestinal microbiota, resulting in susceptibility to opportunistic pathogens, such as Clostridium difficile. Paradoxically, treatment of C. difficile infections (CDI) also involves antibiotic use, leaving patients susceptible to re-infection. This serious health threat has led to an urgent ca...
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