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Many Ys in monotremes: multiple sex chromosomes and sex determination in platypus and echidna

Title
Many Ys in monotremes: multiple sex chromosomes and sex determination in platypus and echidna
Funding
ARC | Discovery Projects
Contract (GA) number
DP0664267
Start Date
2006/01/01
End Date
2010/12/31
Open Access mandate
no
Organizations
-
More information
http://purl.org/au-research/grants/arc/DP0664267

 

  • Widespread divergence of the CEACAM/PSG genes in vertebrates and humans suggests sensitivity to selection.

    Chia Lin Chang; Jenia Semyonov; Po Jen Cheng; Shang Yu Huang; Jae Il Park; Huai-Jen Tsai; Cheng-Yung Lin; Frank Grützner; Yung Kuei Soong; James J Cai; Sheau Yu Teddy Hsu
    Projects: ARC | Many Ys in monotremes: multiple sex chromosomes and sex determination in platypus and echidna (DP0664267)
    In mammals, carcinoembryonic antigen cell adhesion molecules (CEACAMs) and pregnancy-specific glycoproteins (PSGs) play important roles in the regulation of pathogen transmission, tumorigenesis, insulin signaling turnover, and fetal–maternal interactions. However, how these genes evolved and to what extent they diverged in humans remain to be investigated specifically. Based on syntenic mapping of chordate genomes, we reveal that diverging homologs with a prototypic CEACAM architecture–includ...
  • No project research data found
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