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Discovery Projects - Grant ID: DP160102906

Title
Discovery Projects - Grant ID: DP160102906
Funding
ARC | Discovery Projects
Contract (GA) number
DP160102906
Start Date
2016/01/01
End Date
2020/12/31
Open Access mandate
no
Organizations
-
More information
http://purl.org/au-research/grants/arc/DP160102906

 

  • The Curious Case of the OZ439 Mesylate Salt: An Amphiphilic Antimalarial Drug with Diverse Solution and Solid State Structures

    Clulow, Andrew J.; Salim, Malinda; Hawley, Adrian; Gilbert, Elliot P.; Boyd, Ben J. (2018)
    Projects: ARC | Discovery Projects - Grant ID: DP160102906 (DP160102906)
    Efforts to develop orally administered drugs tend to place an exceptional focus on aqueous solubility as this is an essential criterion for their absorption in the gastrointestinal tract. In this work we examine the solid state behavior and solubility of OZ439, a promising single-dose cure for malaria being developed as the highly water-soluble mesylate salt. The aqueous phase behavior of the OZ439 mesylate salt was determined using a combination of small angle neutron and X-ray scattering (S...
  • No project research data found
  • Scientific Results

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