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A protein molecular interaction and localization facility

Title
A protein molecular interaction and localization facility
Funding
ARC | Linkage Infrastructure, Equipment and Facilities
Contract (GA) number
LE100100036
Start Date
2010/01/01
End Date
2010/12/31
Open Access mandate
no
Organizations
-
More information
http://purl.org/au-research/grants/arc/LE100100036

 

  • Kinetics of antigen expression and epitope presentation during virus infection.

    Nathan P Croft; Stewart A Smith; Yik Chun Wong; Chor Teck Tan; Nadine L Dudek; Inge E A Flesch; Leon C W Lin; David C Tscharke; Anthony W Purcell (2013)
    Projects: ARC | A protein molecular interaction and localization facility (LE100100036), NHMRC | Quantification of antigen presentation to CD8 T cells during virus infection (1023141)
    Author Summary A major mechanism for the detection of virus infection is the recognition by T cells of short peptide fragments (epitopes) derived from the degradation of intracellular proteins presented at the cell surface in a complex with class I MHC. Whilst the mechanics of antigen degradation and the loading of peptides onto MHC are now well understood, the kinetics of epitope presentation have only been studied for individual model antigens. We addressed this issue by studying vaccinia v...
  • No project research data found
  • Scientific Results

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