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Discovery Early Career Researcher Award - Grant ID: DE150101863

Title
Discovery Early Career Researcher Award - Grant ID: DE150101863
Funding
ARC | Discovery Early Career Researcher Award
Contract (GA) number
DE150101863
Start Date
2015/01/01
End Date
2017/12/31
Open Access mandate
no
Organizations
-
More information
http://purl.org/au-research/grants/arc/DE150101863

 

  • Chemo- and Regioselective Lysine Modification on Native Proteins.

    Matos, Maria J; Oliveira, Bruno L; Martínez-Sáez, Nuria; Guerreiro, Ana; Cal, Pedro MSD; Bertoldo, Jean; Maneiro, María; Perkins, Elizabeth; Howard, Julie; Deery, Michael John; Chalker, Justin M; Corzana, Francisco; Jiménez-Osés, Gonzalo; Bernardes, Goncalo Jose (2018)
    Projects: ARC | Discovery Early Career Researcher Award - Grant ID: DE150101863 (DE150101863)
    Site-selective chemical conjugation of synthetic molecules to proteins expands their functional and therapeutic capacity. Current protein modification methods, based on both synthetic and biochemical technologies, can achieve site-selectivity, but these techniques often require extensive sequence engineering or are restricted to the N- or C-terminus. Here we show the computer-assisted design of sulfonyl acrylate reagents for the modification of a single lysine residue on native protein sequen...

    Sulfur‐Limonene Polysulfide: A Material Synthesized Entirely from Industrial By‐Products and Its Use in Removing Toxic Metals from Water and Soil

    Crockett, Michael P.; Evans, Austin M.; Worthington, Max J. H.; Albuquerque, Inês S.; Slattery, Ashley D.; Gibson, Christopher T.; Campbell, Jonathan A.; Lewis, David A.; Bernardes, Gonçalo J. L.; Chalker, Justin M. (2015)
    Projects: ARC | Discovery Early Career Researcher Award - Grant ID: DE150101863 (DE150101863)
    Abstract A polysulfide material was synthesized by the direct reaction of sulfur and d‐limonene, by‐products of the petroleum and citrus industries, respectively. The resulting material was processed into functional coatings or molded into solid devices for the removal of palladium and mercury salts from water and soil. The binding of mercury(II) to the sulfur‐limonene polysulfide resulted in a color change. These properties motivate application in next‐generation environmental remediation an...

    Laying Waste to Mercury: Inexpensive Sorbents Made from Sulfur and Recycled Cooking Oils

    Worthington, Max J. H.; Kucera, Renata L.; Albuquerque, Inês S.; Gibson, Christopher T.; Sibley, Alexander; Slattery, Ashley D.; Campbell, Jonathan A.; Alboaiji, Salah F. K.; Muller, Katherine A.; Young, Jason; Adamson, Nick; Gascooke, Jason R.; Jampaiah, Deshetti; Sabri, Ylias M.; Bhargava, Suresh K.;... (2017)
    Projects: ARC | Discovery Early Career Researcher Award - Grant ID: DE150101863 (DE150101863), EC | ReTuBi (692322)
    Abstract Mercury pollution threatens the environment and human health across the globe. This neurotoxic substance is encountered in artisanal gold mining, coal combustion, oil and gas refining, waste incineration, chloralkali plant operation, metallurgy, and areas of agriculture in which mercury‐rich fungicides are used. Thousands of tonnes of mercury are emitted annually through these activities. With the Minamata Convention on Mercury entering force this year, increasing regulation of mercu...
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