Remember Me
Or use your Academic/Social account:


Or use your Academic/Social account:


You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.


Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message


Verify Password:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Баженов, Борис Николаевич; Елисеева, Галина Дмитриевна; Золотарёв, Егор Евгеньевич; Кашевский, Алексей Валерьевич; Сафронов, Александр Юрьевич; Финкельштейн, Борис Львович (2013)
Publisher: Altai State University
Journal: Khimiia rastitel'nogo syr'ia (Chemistry of plant raw material)
Languages: Russian
Types: Article
Subjects: Chemistry, Q, моносукцинат дигидрокверцетина, антиоксидантная активность, циклическая вольтамперометрия, QD1-999, Science, dihydroquercetin monosuccinate, antioxidant activity, cyclic voltammetry
The native antioxidant dihydroquercetin has a wide spectrum of pharmacological properties, however its low solubility make cense for getting the water soluble derivatives maintaining a high antioxidant activity. A possible strategy to get this result could be a hydrophilic moiety (such as succinic acid residue) insertion into the flavonoid molecule. Being more soluble in water the novel synthetic derivative of the bioflavonoid – dihydriquercetin monosuccinate maintains a high antioxidant activity confirmed by means of TEAC method and the voltammetry data. Dihydriquercetin monosuccinate redox transformations on a graphite electrode proving the high antioxidant activity of the studied compound, at the same time demonstrate a complex character. Better understanding of this character is a possible way to the dihydriquercetin monosuccinate redox parameters control under different conditions and/or in the different environments.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1. Internet-versiia Gosudarstvennogo reestra lekarstvennykh sredstv. [Internet-version of the State register of medicines]. URL: http://www.drugreg.ru/Bases/WebReestrQuery.asp. (in Russ.).
    • 2. Plotnikov M.B., Tiukavkina N.A., Plotnikova T.M. Lekarstvennye preparaty na osnove dikvertina. [Medications based on Diquertin.]. Tomsk, 2005. 228 p. (in Russ.).
    • 3. Patent 2088256 (RU). 1997. (in Russ.).
    • 4. Patent 2167414A (UK). 1986.
    • 5. Janeiro P., Conduneanu O., Brett A.M.O. Electroanalysis, 2005, vol. 17, no. 12, pp. 1059-1064.
    • 6. Saito A., Sugisawa A., Umegaki K. Shokuhin Eiseigaku Zasshi, 2001, vol. 42, no. 3, pp. 174-178.
    • 7. Jørgensen L., Madsen H., Thomsen M., Dragsted L., Skibsted L. Free Radical Researsh., 1999, vol. 30, no. 3, pp. 207-220.
    • 8. Matveev D.A., Arbuzova E.A., Kraikivskii P.B., Aprelkova N.F., Khutorianskii V.A., Kriukova K.M. Elektrokhimiia, 2011, vol. 47, no. 9, pp. 1096-1102. (in Russ.).
    • 9. Finkel'shtein B.L., Danilovtseva O.S., Bazhenov B.N., Saibotalov M.Iu. Biotekhnologiia rastitel'nogo syr'ia, kachestvo i bezopasnost' produktov pitaniia: materialy dokladov Vserossiiskoi nauchno-prakticheskoi konferentsii, posviashchennoi 80-letiiu IrGTU. [Biotechnology of plant material, the quality and safety of food products: Materials of All-Russian scientific-practical conference dedicated to the 80th anniversary of Irkutsk State Technical University]. Irkutsk, 2010, pp. 79-83. (in Russ.).
    • 10. Re R., Pellegrini N., Proteggente A., Pannala A., Yang M., Rice-Evans C. Free Radicals Biol. Med., 1999, vol. 26, pp. 1231-1237.
    • 11. Brett C.M.A., Brett A.M.O. Electrochemistry: Principles, Methods and Applications, Oxford, 1993, pp. 174-198.
    • 12. Compton R.G., Banks C.E. Understanding Voltammetry, London, 2011, pp. 107-152.
    • Received May 22, 2012
  • No related research data.
  • No similar publications.

Share - Bookmark

Cite this article