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Publisher: Altay State University
Journal: Himiâ Rastitelʹnogo Syrʹâ
Languages: Russian
Types: Article
Subjects: Chemistry, Q, CE, plants, QD1-999, Science, plants; Ericaceae; calystegines; CE; GC-MS/MS, Ericaceae, calystegines, GC-MS/MS
In Russia, folk-medicinal plants of the family Ericaceae are often used for the treatment of diseases associated with hyperglycemic states. It is known that calystegines, a group of compounds of nortropane alkaloids, have the unique ability of competitive inhibition of glucosidases activity. The objective of this study was to identify calystegines in the chemical composition of plants growing on the islands of Solovetsky Archipelago and belonging to the family Ericaceae: Vaccinium vitis-idaea ( lingonberry or cowberry); Vaccinium myrtillus ( bilberry); Oxycoccus palustris (cranberry); Empetrum hermaphroditum (crowberry, a common name also used for corema); Arctostaphylos uva-ursi ( bearberry) and Ledum palustre (marsh tea, wild rosemary). Preliminary data for the detection of the chemical composition of the studied plants were obtained by capillary zone electrophoresis and further research was carried out by gas chromatography coupled to tandem mass spectrometry. Thus, the presence of calystegines in plant samples of family Ericaceae has been confirmed in the course of the research. It was found that calystegine B2 presents in all samples tested and is dominant. Сalystegine B1 was found in cowberry and cranberry. The presence of calystegine B3 was convincingly confirmed only in lingonberry. The presence of calystegines in the chemical composition of studied plants is one of the reasons of explaining their use in folk medicine for treating of hyperglycemic states.