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Publisher: Altai State University
Journal: Khimiia rastitel'nogo syr'ia (Chemistry of plant raw material)
Languages: Russian
Types: Article
Subjects: настойка календулы; флавоноиды; тонкослойная хроматография; валидация, Marigold tincture, flavonoids, thin-layer chromatography, validation
The thin-layer chromatography method of flavonoids’ identification in the Marigold tincture was developed. The validation characteristics such as specificity, robustness, precision were studied. During robustness study the influences of chamber’s type, stationary phase, development distance, conditions of dryness and derivatization, stability of the test solution during analysis were investigated. The optimal conditions of chromatography analysis were investigated. The specificity of method of flavonoids’ determination was proved with the reference standard rutin, Marigold tincture, prepared from authentic herbal raw material, and the adulteration. The precision of the method on the same and on the different plates, the interlaboratory precision were studied. The possibility of usage developed method for standardization of Marigold tincture in the condition of the quality control lab was proved. For assuring specificity of identification of Marigold tincture, the determination of characteristic substances for Marigold flower – calendulosides, is reasonable. 
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

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    • Received June 16, 2014
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