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Kalinkevich, Katerina; Karandashov, Vladimir; Ptitsyn, Leonid (2013)
Publisher: Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования «Алтайский государственный университет»
Journal: Химия растительного сырья
Languages: Russian
Types: Article
Subjects: Chemistry, Q, plant extracts, QD1-999, Science, anti-inflammatory, TNF-α ASSAY, anti-inflammatory; plant extracts; TNF-α assay; PGE2 assay, PGE2 assay

Classified by OpenAIRE into

mesheuropmc: lipids (amino acids, peptides, and proteins)

The effects of the ethanolic extracts of 105 plants used in Russian traditional medicine, 26 vegetables and fruits and 2 mushrooms on the release of tumor necrosis factor α (TNF-α) and prostaglandin E2 (PGE2) in lipopolysaccharide (LPS)-stimulated differentiated human acute monocytic leukemia THP-1 cells were studied using TNF-α and PGE2 assays, respectively. We found that 16 plant extracts inhibited TNF-α production and 15 extracts decreased PGE2 release in the cells in a concentration-dependent manner. Guilder rose, tansy, shrubby cinquefoil, wintergreen and prince's pine, the last two of which belong to the Pyrolaceae family, notably inhibited the levels of both of the inflammatory mediators.

  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

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