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Elsom, Giles K.; Freeman, Julia A.; Hide, Denis; Salmon, David M. (2011)
Publisher: Microbial Ecology in Health and Disease
Journal: Microbial Ecology in Health and Disease
Languages: English
Types: Article
Subjects:

Classified by OpenAIRE into

mesheuropmc: food and beverages
The effect of Lactobacillus acidophilus on the growth of Candida albicans and Escherichia coli was investigated in the presence of aqueous extract of garlic. L. acidophilus, a homofermentative organism, produced lactic acid that lowered the pH of the culture medium, resulting in a reduction in numbers of C. albicans and E. coli in mixed culture. When the extract of garlic was added at a concentration of 2.56 mg total thiosulphinate/ml for C. albicans in mixed culture and at a concentration of 5.12 mg total thiosulphinate/ml for E. coli in mixed culture, the reduction in cell numbers of both C. albicans and E. coli was accelerated. After 4 h no C. albicans cells were countable, while E. coli cells were absent after 24 h. Several commercial preparations of garlic, which included oil macerates, pastes, tablets and powders, were examined for their anticandidal activity and for their ability to inhibit platelet aggregation. The activity of the preparations was assayed by determining the concentration of total thiosulphinates present in each brand. Only the garlic tablet formulation exhibited good anticandidal and antiplatelet activity, whereas all the other preparations possessed virtually no anticandidal and antiplatelet properties.Key words: anticandidal, antiplatelet, aqueous extract of garlic, microbial flora, probiotic, mixed culture, commercial preparations of garlic.
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    • 1. Moneysmith M. Lactobacillus acidophilus ? Better Nutrition 2001; 63: 28.
    • 2. Barilla J. The balance of the bugs. Better Nutrition 1999; 61: 54.
    • 3. Schaeffer AJ, Jones JM, Dunn JK. Association of in vitro Escherichia coli adherence to vaginal and buccal epithelial cells with susceptibility of women to recurrent urinary-tract infections. N Engl J Med 1981; 304: 1062 /6.
    • 4. Ankri S, Mirelman D. Antibacterial properties of allicin from garlic. Microbes and Infections 1999; 1: 125 /9.
    • 5. Farbman KS, Barrett ED, Bolduc GR. Antibacterial activity of garlic and onions: a historical perspective. Pediatr Infect Dis J 1993; 7: 613 /4.
    • 6. Wills ED. Enzyme inhibiton by allicin, the active principle of garlic. Biochem J 1956; 63: 514 /20.
    • 7. Elsom GKF, Hide D, Salmon DM. An antibacterial assay of aqueous extract of garlic against anaerobic/microaerophilic and aerobic bacteria. Microb Ecol Health Dis 2000; 12: 81 /4.
    • 8. Rees LP, Minney SF, Plummer JH, Slater JH, Skyrme DA. A quantitative assessment of the antimicrobial activity of garlic (Allium sativum ). World Journal of Microbiology and Biotechnology 1993; 9: 303 /7.
    • 9. Lawson LD, Ransom DK, Hughes BG. Inhibition of whole blood platelet-aggregation by compounds in garlic clove extracts and commercial garlic products. Thromb Res 1992; 65: 141 /56.
    • 10. Han J, Lawson L, Han G, Han P. A spectrophotometric method for quantitative determination of allicin and total thiosulphinates. Anal Biochem 1995; 225: 157 /60.
    • 11. Miles AA, Misra SS. The estimation of the bactericidal power of blood. J Hyg Camb 1938; 38: 732.
    • 12. Elsom GKF, Hide D. Susceptibility of methicillin-resistant Staphylococcus aureus to tea tree oil and mupirocin. J Antimicrob Chemother 1999; 43: 427 /8.
    • 13. Salmon DM. Optimisation of platelet aggregometry utilising microtitreplate technology and integrated software. Thromb Res 1996; 84: 213 /6.
    • 14. Reid G. Probiotic agents to protect the urogenital tract against infection. Am J Clin Nutr 2001; 73 (2 Suppl): 437S /443S.
    • 15. Makheja AN, Bailey JM. Antiplatelet constituents of garlic and onions. Agents Actions 1990; 29: 360 /3.
    • 16. Weisenberger H, Grube H, Koeing E, Pelzer H. Isolation and identification of the platelet aggregation inhibitor present in the onion: Allium cepa . FEBS Lett 1972; 26: 105 /8.
    • 17. Ghannoum MA. Studies on the anticandidal mode of action of Allium sativum (garlic). J Gen Microbiol 1988; 134: 2917 /24.
    • 18. Kyung KH, Park KS, Kim YS. Isolation and characterisation of bacteria resistant to the antimicrobial activity of garlic. J Food Sci 1996; 61: 226 /9.
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