LOGIN TO YOUR ACCOUNT

Username
Password
Remember Me
Or use your Academic/Social account:

CREATE AN ACCOUNT

Or use your Academic/Social account:

Congratulations!

You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.

Important!

Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message

CREATE AN ACCOUNT

Name:
Username:
Password:
Verify Password:
E-mail:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Abimiku, A. G.; Borriello, S. P. (2011)
Publisher: Microbial Ecology in Health and Disease
Journal: Microbial Ecology in Health and Disease
Languages: English
Types: Article
Subjects:
A mutant of Campylobacter jejuni strain 81116 arose spontaneously during laboratory subculture and was given the identification code of Mut. A/81116. Unlike the parent strain, this mutant lacked the ability to colonise the gut of 5-day-old infant mice. Comparative analysis of both strains showed that the mutant had retained the biochemical reactions, the Lior and Penner serotype, the flagella, and the SDS-PAGE protein profile of the parent strain. However, the mutant had reduced motility, could not colonise the gut of adult Balb/C mice following an intraperitoneal live vaccination and, unlike the parent strain, did not cause resorption of fetuses in pregnant Balb/C mice. In addition, immunoblotting showed minor differences in the 26-31 kDa region. Vaccines made from the mutant had reduced efficacy. The mutant has been lodged with the National Collection of Type Cultures Colindale, and designated NCTC 12189.Keywords - Campylobacter jejuni; Infant mouse colonisation.

Share - Bookmark

Cite this article

Collected from