LOGIN TO YOUR ACCOUNT

Username
Password
Remember Me
Or use your Academic/Social account:

CREATE AN ACCOUNT

Or use your Academic/Social account:

Congratulations!

You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.

Important!

Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message

CREATE AN ACCOUNT

Name:
Username:
Password:
Verify Password:
E-mail:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Larsen, T.; Fiehn, N.-E.; Østergaard, E. (2011)
Publisher: Microbial Ecology in Health and Disease
Journal: Microbial Ecology in Health and Disease
Languages: English
Types: Article
Subjects:
Longo Vital® herbal tablets have been shown to have a protective effect against periodontal bone loss in rats. This may be ascribed either to a previously demonstrated immuno-stimulatory effect of the tablets, to an antimicrobial effect of the herbs or to a combination of both. In the present study the in vitro susceptibility of 12 dental plaque bacteria to six individual herbs included in Longo Vital® was determined by a broth dilution method. Paprika, rosemary leaves and peppermint inhibited two thirds of the tested bacteria at 2.8-45 mg/ml, 0.75-12 mg/ml and 3-24 mg/ml corresponding to 0.8-12.5 per cent, 1.6-25 per cent and 12.5-100 per cent of the recommended daily dose, respectively. A combination of paprika and rosemary leaves tested towards five susceptible bacteria revealed a decreased inhibitory effect on two of these bacteria, especially of Actinobacillus actinomycetemcomitans to paprika, but conversely a pronounced increase in susceptibility of Peptostreptococcus anaerobius, Porphyromonas gingivalis and Prevotella intermedia now susceptible to 0.01-0.70 mg/ml of each herb, corresponding to 0.02-0.2 per cent of the recommended daily dose. The active ingredients of the herbs, however, and the concentrations of these obtained in blood and periodontal tissues after ingestion of Longo Vital® are not known.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • (1987). Structural determinants of activity of chlorhexidine and alkyl bisbiguanides against the human oral flora. Journal of Dental Research 66, 1099-1 106.
    • Dold H, Knapp A. (1948). a b e r die antibakterielle Wirkung von Gewiirzen. Zeitschrift fur Hygiene und Infektions-Krankenheiten 128, 696706.
    • Dzink JL, Socransky SS. (1985). Comparative in vitro activity of sanguinarine against oral microbial isolates. Antimicrobial Agents and Chemotherapy 27, 663-665.
    • Ericsson HM, Sherris JC. (1971). Antibiotic sensitivity testing. Report of an international collaborative study. Acta Pathologica Microbiologica Immunologica Scandinavica Section B (Suppl. no.
    • 5. Fiehn N-E. (1987). Biochemical characterization of nine oral small-sized spirochete strains containing one endoflagellum from each cell-end. Acta Pathologica Microbiologica Immunologica Scandinavica Section B 95, 309-3 14.
    • 6. Fiehn N-E, Westergaard J. (1986). Nutrient and environmental growth factors for eight small-sized oral spirochetes. Scandinavian Journal of Dental Research 94, 208-218.
    • 7. Klausen B, Apostolopoulos A, Stoltze K, Norgaard F. (1993). Effect of Longo Vital treatment on development of periodontal disease in rats. Scandinavian Journal of Dental Research 101, 33-36.
    • 8. Marsh PD. (1991). Dentrifices containing new agents for the control of plaque and gingivitis: microbiological aspects. Journal of Clinical Periodontology 18, 462-467.
    • 9. Meeker HG, Linke HA. (1988). The antibacterial action of eugenol, thyme oil, and related essential oils used in dentistry. Compendium 9, 32-41.
    • 10. Pedersen A, Hougen HP, Klausen B. (1990). Longo Vital in the prevention of recurrent aphthous ulceration. Journal of Oral Pathology and Medicine 19, 371-375.
    • 11. Pedersen A, Klausen B, Hougen HP, Ryder L, Winther K. (1990). Immunomodulation by LongoVital in patients with recurrent aphthous ulceration. Journal of Oral Pathology and Medicine 19, 376380.
    • 12. Saeki Y, Ito Y, Shibata M, Sat0 Y, Okuda K, Takazoe I. (1989). Antimicrobial action of natural substances on oral bacteria. Bulletin of Tokyo Dental College 30, 129-135.
    • 13. Scheie AA. (1989). Modes of action of currently known chemical anti-plaque agents other than chlorhexidine. Journal of Dental Research 68 (Spec. Iss.), 1609-1 616.
    • 14. Shapiro S, Meier A, Guggenheim B. (1994). The antimicrobial activity of essential oils and essential oil components towards oral bacteria. Oral Microbiology and Immunology 9, 202-208.
  • No related research data.
  • No similar publications.

Share - Bookmark

Cite this article

Collected from