Remember Me
Or use your Academic/Social account:


Or use your Academic/Social account:


You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.


Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message


Verify Password:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Erlanson-Albertsson, Charlotte (2000)
Publisher: Co-Action Publishing
Journal: Food & Nutrition Research
Languages: English
Types: Article
Appetite regulation and feeding behaviour are critical for survival. Through appetite regulation the proper amounts of fat, carbohydrate and protein are provided through specific signals, as has been demonstrated both in rodents and in man. Although feeding is necessary to provide energy, it also leads to severe perturbations in the homeostasis of the body. To help the body to maintain homeostasis various pre-meal events occur, such as the cephalic phase secretion of pancreatic juice, the production of satiety signals and the production of heat. The latter probably involves the action of uncoupling proteins present in the intestine. The diet-induced thermogenesis is hence important for achieving energy balance in the body. The increasing prevalence of obesity in the Western world is suggested to be a consequence of the overflow of tasty high-fat and sweet food items, which after ingestion override the original rules that we were once constructed for. Keywords: diet-induced thermogenesis, leptin, NPX opiates, uncouling protein
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • Levine S BC: Why do we eat? A neural systems approach. Ann Rev Nutr 1997;17:597-619.
    • Amsterdam: Elsevier Science, 1999:287-313.
    • Mayer J: Bulletin of the New England Medical Center, Volume XIV, April-June 1952: The glucostatic theory of regulation of food intake and the problem of obesity (a review) [classical article]. Nutr Rev 1991;49:46-8.
    • Kral JG: Surgical reduction of adipose tissue in the male Sprague-Dawley rat. Am J Physiol 1976;231:1090-6.
    • Beck B, Jhanwar-Uniyal M, Burlet A, Chapleur-Chateau M, Leibowitz SF, Burlet C: Rapid and localized alterations of neuropeptide Y in discrete hypothalamic nuclei with feeding status. Brain Res 1990;528:245-9.
    • Stanley BG, Daniel DR, Chin AS, Leibowitz SF: Paraventricular nucleus injections of peptide YY and neuropeptide Y preferentially enhance carbohydrate ingestion. Peptides 1985;6: 1205-11.
    • 7. Davies L, Marks JL: Role of hypothalamic neuropeptide Y gene expression in body weight regulation. Am J Physiol 1994;266:R1687-91.
    • 8. Wilding JP, Ajala MO, Lambert PD, Bloom SR: Additive effects of lactation and food restriction to increase hypothalamic neuropeptide Y mRNA in rats. J Endocrinol 1997;152:365-9.
    • 9. Morley JE, Levine AS, Yim GK, Lowy MT: Opioid modulation of appetite. Neurosci Biobehav Rev 1983;7:281-305.
    • 10. Barton C, Lin L, York DA, Bray GA: Differential effects of enterostatin, galanin and opioids on high-fat diet consumption. Brain Res 1995;702:55-60.
    • 11. Drewnowski A, Krahn DD, Demitrack MA, Nairn K, Gosnell BA: Taste responses and preferences for sweet high-fat foods: evidence for opioid involvement. Physiol Behav 1992; 51:371-9.
    • 12. Welch CC, Kim EM, Grace MK, Billington CJ, Levine AS: Palatability-induced hyperphagia increases hypothalamic Dynorphin peptide and mRNA levels. Brain Res 1996;721:126-31.
    • 13. Sarles H, Dani R, Prezelin G, Souville C, Figarella C: Cephalic phase of pancreatic secretion in man. Gut l968;9:214-21.
    • 14. Moran TH, Baldessarini AR, Salorio CF, Lowery T, Schwartz GJ: Vagal afferent and efferent contributions to the inhibition of food intake by cholecystokinin. Am J Physiol 1997;272:R1245-51.
    • 15. Naslund E, Barkeling B, King N, et al: Energy intake and appetite are suppressed by glucagonlike peptide- 1 (GLP- 1) in obese men. Int J Obes Relat Metab Disord 1999;23:304-11.
    • 16. Green ED, Maffei M, Braden VV, et al: The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7. Genome Res 1995;5:5-12.
    • 17. Erickson JC, Hollopeter G, Palmiter RD: Attenuation of the obesity syndrome of oblob mice by the loss of neuropeptide Y [see comments]. Science 1996;274:1704-7.
    • 18. Montague CT, Farooqi IS, Whitehead JP, et al: Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 1997;387:903-8.
    • 19. Maffei M, Halaas J, Ravussin E, et al: Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weightreduced subjects. Nat Med 1995;l:1155-61.
    • 20. Erlanson-Albertsson C, York D: Enterostatin--a peptide regulating fat intake. Obes Res 1997;5:360-72.
    • 21. Erlanson-Albertsson C: Enterostatin -apeptide regulating fat intake. Scand J NutrINaringsforskning l994;38: 11-4.
    • 22. Berger K, Winze11MS, Erlanson-Albertsson C: Binding of enterostatin to the human neuroepithelioma cell line SK-N-MC. Peptides 1998;19:1525-31.
    • 23. Himms-Hagen J: Role of brown adipose tissue thermogenesis in control of thermoregulatory feeding in rats: a new hypothesis that links thermostatic and glucostatic hypotheses for control of food intake. Proc Soc Exp Biol Med 1995;208:159-69.
    • 24. De Vries J, Strubbe JH, Wildering WC, Gorter JA, Prins AJ: Patterns of body temperature during feeding in rats under varying ambient temperatures. Physiol Behav l993;53:229-35.
    • 25. Ricquier D, Bouillaud F: The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP. Biochem J 2000;345 Pt 2:161-79.
    • 25. Scarpace PJ, Nicolson M, Matheny M: UCP2, UCP3 and leptin gene expression: modulation by food restriction and leptin. J Endocrinol 1998;159:349-57.
    • 27. Kuskowska-Wolk A, Bergstrom R: Trends in body mass index and prevalence of obesity in Swedish men 1980- 89. J Epidemiol Community Health 1993;47:103-8.
    • 28. Kuskowska-Wolk A, Bergstrom R: Trends in body mass index and prevalence of obesity in Swedish women 1980-89. J Epidemiol Community Health 1993;47:195-9. 0
  • No related research data.
  • No similar publications.

Share - Bookmark

Cite this article

Collected from