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Elmehdawi RR, Elmajberi SJ (2009)
Publisher: Co-Action Publishing
Journal: Libyan Journal of Medicine
Languages: English
Types: Article
Background: Diabetes mellitus and gall bladder stones are both common and costly diseases. Increasing age, female gender, overweight, familial history of the disease and type 2 diabetes mellitus is all associated with an increased risk of gallstones. Several studies from around the world reported an increased prevalence of gall bladder stones in patients with diabetes mellitus. Aims and objectives: The aim of this study was to define the frequency of gall bladder stones among Libyan diabetics and to evaluate the possible associated risk factors in these patients. Patients and methods: A case-control study was performed during 2007 at Benghazi Diabetes and endocrinology Center. The study involved 161 randomly selected type-2 diabetic patients under regular follow up at the center, and 166 age and sex matched non-diabetic outpatients at the 7th of October teaching hospital. Real-time abdominal ultrasound was performed by two radiologists to examine the abdomen after an overnight fast. Results: About 40% of the diabetic cohort had gall bladder stones as compared to 17.5% of non-diabetic patients. Females were significantly more affected than males. Patients with gall bladder stones were significantly older and had a significantly higher body mass index than those without stones. Conclusion: The prevalence of gallstones in Libyan diabetic patients is higher than the rates reported in other parts of the world. Libyan diabetic patients with gallstones tend to be older and more obese than those without gallstones. Duration of diabetes mellitus and type of treatment does not seem to influence the frequency of gall bladder stones among Libyan diabetics. Key words: Diabetes, Gallstone, Gallbladder, Obesity, Epidemiology, Libya
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    • 1. Jorgensen T. Epidemiology and gallstones Ugeskr Laeger. 2005; 167(24):2610-3.
    • 2. Abdulwahab KMS and Karim A. changing pattern of surgical diseases in Benghazi. Garyounis Med J 1995 ;18:29-31.
    • 3. Elrefai N, Abuzeid I, Elraeid R, Gargoom A. Prevalence of gall bladder stones post-cholecystectomy in diabetic patients. Jamahiriya Med J. 2007 ;7(1):42-4.
    • 4. Hahm JS, Park JY, Park KG, et al. Gallbladder motility in diabetes mellitus using real time ultrasonography. Am J Gastroenterol 1996; 91:2391.
    • 5. Ruhl CE, Everhart JE. Association of diabetes, serum insulin, and C-peptide with gallbladder disease. Hepatology 2000; 31:299.
    • 6. Pagliarulo M, Fornari F, Fraquelli M, et al. Gallstone disease and related risk factors in a large cohort of diabetic patients. Dig Liver Dis. 2004; 36(2):130-4.
    • 7. Chapman BA, Wilson IR, Frampton CM, et al. Prevalence of gallbladder disease in diabetes mellitus. Dig Dis Sci. 1996; 41(11):2222-8.
    • 8. Liu CM, Tung TH, Liu JH, Lee WL, Chou P. A community-based epidemiologic study on gallstone disease among type 2 diabetics in Kinmen, Taiwan. Dig Dis. 2004; 22(1):87-91.
    • 9. Attili AF, Carulli N, Roda E, et al. Epidemiology of gallstone disease in Italy: Prevalence data of the multicenter Italian study on cholelithiasis (M.I.COL.). Am J Epidemiol 1995; 141:58.
    • 10. Everson GT. Pregnancy and gallstones. Hepatology 1993; 17:159.
    • 11. Mabee TM, Meger P, DerBesten L, Mason EE. The mechanism of increased gallstone formation in obese human subjects. Surgery 1976; 79:460.
    • 12. Jorgensen T. Prevalence of gallstones in a Danish population. Am J Epidemiol 1987; 126:912.
    • 13. Attili AF, De Santis A, Attili F, Roda E, Festi D, Carulli N. Prevalence of gallstone disease in first-degree relatives of patients with cholelithiasis. World J Gastroenterol 2005; 11(41):6508-11.
    • 14. Thijs C, Leffers P, Knipschild P. Oral contraceptive use and the occurrence of gallstone disease--a case-control study. Prev Med 1993; 22:122.
    • 15. Pannwitz H, Berndt H, N├╝rnberg D. Prevalence of cholelithiasis in relation to use of hormonal contraceptives. Gastroenterol J 1990; 50(2):78-81.
    • 16. Strom BL, Tamragouri RN, Morse ML, et al. Oral contraceptives and other risk factors for gallbladder disease. Clin Pharmacol Ther 1986; 39:335.
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