Remember Me
Or use your Academic/Social account:


Or use your Academic/Social account:


You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.


Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message


Verify Password:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Beighton, D.; Whiley, R. A.; Homer, K. A. (2011)
Publisher: Microbial Ecology in Health and Disease
Journal: Microbial Ecology in Health and Disease
Languages: English
Types: Article
The ability of oral streptococcal species to bind transferrin was determined using an assay system in which the binding of fluorescein isothiocyanate-labelled transferrin was monitored by measuring the decrease in fluorescence using excitation and emission wavelengths of 495 nm and 525 nm, respectively. Transferrin was bound by all species tested but Streptococcus oralis and Streptococcus mitis exhibited the greatest affinity and the mutans streptococci the least. Transferrin binding to S. oralis was inhibited by fetuin but not by N-acetylneuraminic acid or bovine N-acetylneuramin lactose. Transferrin binding by S. oralis and S. mitis may be involved in their initial attachment to the tooth surface and in their nutrition.Keywords: Transferrin binding; Oral streptococci; Streptococcus orah; Siak acid.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1. Andrewes FW, Horder TJ (1906). A study of the streptococcipathogenicfor man. Lancet ii, 708-71 3.
    • 2. Babu JP, Dabbous MK (1986). Interaction of salivary fibronectin with oral streptococci. Journaf of Dental Research 65, 1 0 9 4 1100.
    • 3. Babu JP, Beachey EH, Hasty DL, Simpson WA (1 986). The isolation and characterization of a 60- kilodalton salivary glycoprotein with agglutinating activity against strains of Streptococcus mutans. Infection and Immunity 51,405413.
    • 4. Beighton D, Homer KA (1989). Protease activity of mutans streptococci.Caries Research 23,448.
    • 5. Brill N, Bronnestam R (1960). Immuno-electrophoretic study of tissue fluid from gingival pockets. Acta Odontologica Scandinavica 18,95-100.
    • 6. Carlsson J, Herrmann BF, Hofling JF, Sundqvist GJ (1984). Degradation of albumin, haemopexin, haptoglobulin and transferrin by black-pigmented Bacteroides species. Journal of Medical Microbiology 18,3946.
    • 7. Coykendall AL (1977). Proposal to elevate the subspecies of Streptococcus mutans to species status based on their molecular composition. International Journal Systematic Bacteriology 27,2630.
    • 8. Coykendall AL (1983). Streptococcus sobrinus nom. rev. and Streptococcus ferus nom. rev.: habitat of these and other mutans streptococci. International Journal Systematic Bacteriology 33,883-885.
    • 9. Coykendall AL (1989). Classification and identification of the viridans streptococci. Clinical Microbiological Reviews 2,3 15-328.
    • 10. Curtis MA, Griffiths GS, Price SJ, Coulhurst SK, Johnson NW (1988). The total protein concentration of gingival crevicular fluid. Variation with sampling time. Journal of Clinical Periodontology 15,628-632.
    • 11. Douglas CWI (1983). The binding of human salivary alpha-amylase by oral strains of streptococcal bacteria. Archives of Oral Biology 28,567-573.
    • 12. Douglas CWI, Pease AA, Whiley RA (1990). Amylase-binding as a discriminator among oral streptococci. FEMS Microbiology Letters 66, 193- 198.
    • 13. Gabriel 0, Heeb MJ, Hinrichs M (1985). Interactions of the surface adhesins of oral Actinomyces spp. with mammalian cells. In: Mergenhagen SE, Rosan B (eds) Molecular Basis of Oral Microbial Adhesion, American Society for Microbiology, Washington, DC, pp 45-52.
    • 14. Kilian M, Mikkelsen L, Henrichsen J (1989). Taxonomic study of viridans streptococci: description of Streptococcus gordonii sp. nov. and amended descriptions of Streptococcus sanguis (White and Niven 1946), Streptococcus oralis (Bridge and Sneath 1982), and Streptococcus mitis (Andrewes and Horder 1906). International Journal of Systematic Bacteriology 39,471484.
    • 15. Levine MJ, Herzberg MC, Levine MS, Ellison SA, Stinson MW, Li HC, Van Dyke T (1978). Specificity of saliva-bacteria interactions: role of terminal sialic acid residues in the interaction of salivary glycoproteins with Streptococcus sanguis and Streptococcus mutans. Infection and Immunity 19, 107-1 15.
    • 16. Levine MJ, Tabak LA, Reddy M, Mandel ID (1985). Nature of salivary pellicles in microbial adherence: role of salivary mucins. In: Mergenhagen SE, Rosan B (eds) Molecular Basis of Oral Microbial Adhesion, American Society for Microbiology, Washington DC, pp 125-130.
    • 17. Montreuil J, Bouquelet S, Debray H, Fournet B, Spik G, Strecker G (1986). Glycoproteins. In: Chaplin MF, Kennedy J F (eds) Carbohydrate Analysis: A Practical Approach, IRL Press, Oxford, pp 143-204.
    • 18. Morris EJ, McBride BC (1983). Aggregation of Streptococcus sanguis by a neuraminidase-sensitive component of serum and crevicular fluid. Infection and Immunity 42,1073-1080.
    • 19. Rinderknecht H (1962). Ultra-rapid labelling of proteins. Nature 193, 167-168.
    • 20. Whiley RA, Hardie J M (1988). Streptococcus vestibularis sp. nov. from the human oral cavity. International Journal Systematic Bacteriology 38, 335-3 39.
    • 21. Whiley RA, Hardie JM (1989). DNA-DNA hybridization studies and phenotypic characteristics of strains within the 'Streptococcus miller? group. Journal of General Microbiology 135, 2623-2633.
    • 22. Williams RC, Gibbons R G (1972). Inhibitors of bacterial adherence by secretory immunoglobulin A: a mechanism of antigen disposal. Science 177, 697-699.
  • No related research data.
  • No similar publications.

Share - Bookmark

Cite this article

Collected from