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Yasui, H.; Nagaoka, N.; Mike, A.; Hayakawa, K.; Ohwaki, M. (2011)
Publisher: Microbial Ecology in Health and Disease
Journal: Microbial Ecology in Health and Disease
Languages: English
Types: Article

Classified by OpenAIRE into

mesheuropmc: digestive system, fluids and secretions
An in vitro screening test using the murine Peyer's patch cell culture method was developed for detection of bifidobacteria which induce large quantities of IgA. Bifidobacteria grown for 48 h were added at a dose corresponding to an absorbance value of 0.275 at 660 nm to BALB/c mouse Peyer's patch cells, and 7 days later the quantities of IgA antibody in the culture supernatants were measured by an ELISA method. With this screening test, three strains of bifidobacteria capable of inducing large quantities of IgA were selected from 120 strains isolated from human faeces and identified as Bifidobacterium breve (two strains) and B. longum (one strain). When one of the three strains (B. breve YIT 4064) was administered orally along with cholera toxin (CT) into mice, the amount of anti-CT IgA antibody in faeces and anti-CT IgA antibody production and proliferation in Peyer's patch cells tended to be greater and were significantly greater, respectively, than after administration of only CT or CT and B. breve Ka-6, which did not induce IgA.Keywords: Bifidobacterium; Andjuvant activity; Peyer's patch; IgA; Cholera toxin.
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    • European Journal of Immunology 4,701-704. 2. Cash RA, Music SI, Libonati JP, Craig JP, Pierce
    • N F , Hornich RB. (1974). Response of man t o infec-
    • tion with Vibrio cholerae. I1 Protection from illness
    • Injectious Diseases 130,325-333.
    • Elson CO,Ealding W, Lefkowitz J . (1984). A lavage
    • Immunological Methods 67, 101-1 08.
    • SM, McGhee J R . (1982). An enzymatic method
    • Immunological Methods 4 8 , 3 3 4 . 5. Homma N. (1974). Intestinal flora of infants and
    • Society 27, 12661275. 6. LawrenceKS, David F K . (1989). Reduction ofintes-
    • secretory immunity. Science 243, 1462-1464. 7. Mishell RI, Dutton RW. (1967). Immunization of
    • Journal of Experimental Medicine 126,423442. 8. Mitsuoka T, Kaneuchi C . (1977). Ecology of
    • Nutrition 30, 1799- 18 10. 9. Moreau MC, Ducluzeau R, Guy-Grand D. Muller
    • MC. (1978). Increase in the population of duodenal
    • of intestinal origin. Infection and Immunity 21,
    • 532-539. 10. Moreau MC, Ducluzeau R, Muller MC, Raibaud P.
    • (1985). Effect of an Escherichia coli strain on intesti-
    • Biological Research 181,391-394. 1 1 Naqi SA, Cook J, Sahin N . (1984). Distribution of
    • Veterinary Research 45,2 193-2 195. 12. Ogra PL, Karzon DT. (1969). Distribution of polio-
    • with poliovaccine. Journal of Immunology 102,
    • 1423-1 430. 13. Owen RL. (1977). Sequential uptake of horseradish
    • 1 2 , 4 4 0 4 5 1. 14. Pierce N F , Cray WC, Engel PF. (1980). Antitoxin
    • cholera toxin. Infection and Immunity 27,632-637. 15. Poupard JA, Husain I, Norris RF. (1973). Biology
    • and bifidobacteria. Bacteriological Reviews 37,
    • 13k16.5. 16. Stokes CR, Soothill JF, Turner MW. (1975).
    • Immune exclusion is a function of IgA. Nmture 255,
    • 745-746. 17. Svennerholm AM, Jertborn M, Gothefors L, Karim
    • AMMM, Sack DA, Hormgren J . (1984). Mucosal
    • Diseases 149,884893. 18. Swarbrick ET, Stokes CR, Soothill JF. (1979).
    • tolerance. Gut 20, 121-125. 19. Yamazaki S, Kamimura H, Momose H, Kawashima
    • T, Ueda K. (1982). Protective effect of Bifidobac-
    • Escherichia coli. Bifidobactrria Microjora 1,55-59. 20. Yasui H, Mike A, Ohwaki M. (1989). Immuno-
    • administration. Journal of Dairy Science 72,30-35.
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