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Routledge, Sarah J.; Poyner, David R.; Bill, Roslyn M. (2014)
Languages: English
Types: Article
Present research has found that antifoams can have a broad range of effects upon bioprocesses, both on the culture environment and upon the cells themselves.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1. Etoc A, Delvigne F, Lecomte JP, Thonart P. Foam Control in Fermentation Bioprocess: From simple aeration tests to bioreactor. Appl. Biochem. Biotechnol. 129-132, 392-404 (2006).
    • 2. Christiano SP, Fey KC. Silicone antifoam performance enhancement by nonionic surfactants in potato medium. J. Ind. Microbiol. Biotechnol. 30, 13-21 (2003).
    • 3. Koller K. Foam control in fermentation processes: while chemical defoamers are ideal for foam prevention, mechanical systems provide gentle defoaming through a combination of foam destruction and foam recycling. Chemical Engineering, 1 August (2004).
    • 4. Varley J, Brown A, Boyd R, Dodd P, Gallagher S. Dynamic multipoint measurement of foam behaviour for a continuous fermentation over a range of key process variables. Biochem. Eng. J. 20, 61-72 (2004).
    • 5. Holmes W, Smith R, Bill R. Evaluation of antifoams in the expression of a recombinant FC fusion protein in shake flask cultures of Saccharomyces cerevisiae. Microb. Cell Fact. 5, 30 (2006).
    • 6. Pelton R, Flaherty T. Defoamers: linking fundamentals to formulations. Polym. Int. 52, 469-485 (2003).
    • 7. Höfer R. Struktol Foams and Foam Control. (2008).
    • 8. Bartsch O. Über Schaumsysteme (1942).
    • 9. Rosen J, Solash J. Factors affecting initial foam height in the Ross-Miles foam test. J. Am. Oil Chem. Soc. 46, 399-402 (1968).
    • 10. Morao A, Maia C, Fonseca M, Vasconcelos J, Alves S. Effect of antifoam addition in gas-liquid mass transfer in stirred fermenters. Bioprocess Engineering 20, 165-172 (1999).
    • 11. Routledge SJ, Hewitt CJ, Bora N, Bill RM. Antifoam addition to shake flask cultures of recombinant Pichia pastoris increases yield. Microb. Cell Fact. 10(17), 1-11 (2011).
    • 12. Koch V, Rüffer H, Schügerl K, Innertsberger E, Menzel H, Weis J. Effect of antifoam agents on the medium and microbial cell properties and process performance in small and large reactors. Process Biochemistry 30, 435-446 (1995).
    • 13. Palomares LA, Estrada-Mondaca S, Ramírez OT. Production of recombinant proteins challenges and solutions. Methods Mol. Biol. 2, 15-51 (2004).
    • 14. Mukaiyama H, Giga-Hama Y, Tohda H, Takegawa K. Dextran sodium sulphate enhances secretion of recombinant human transferrin in Schizosaccharomyces pombe. Appl. Microbiol. Biotechnol. 85, 155-164 (2009).
    • 15. Routledge SJ. Beyond de-foaming: the effects of antifoams on bioprocess productivity. Comput. Struct. Biotechnol. J. 3(4), e201210014 (2012).
    • 16. Batra J, Beri D, Mishra S. Response surface methodology based optimization of β-glucosidase production from Pichia pastoris. Appl. Biochem. Biotechnol. 172(1), 380-393 (2013).
    • 17. Andersson E, Ramgren M, Hahn-Hagerdal B. The Influence of PEG on α-amylase production with Bacillus species. Biochemical Engineering 506 , 613-616 (1987).
    • 18. Pawiroharsono S, Naji B, Bonaly R, Tonetti F, Chasseboeuf C, Richter P. Permeability and membrane sterol distribution in Saccharomyces uvarum and Kluyveromyces bulgaricus grown in presence of polyoxyalkylene lycol-oleic acid condensates. Appl. Microbiol. Biotechnol. 27, 181-185 (1987).
    • 19. Routledge SJ, Bill RM. The effect of antifoam addition on protein production yields. In: Recombinant Protein Production in Yeast, Bill RM. Humana Press, NY, USA, 87-97 (2012).
    • 20. Mcgregor WC, Weaver JF, Tansey SP. Antifoam effects on ultrafiltration. Biotechnol. Bioeng. 31(4), 385-389 (2004).
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