LOGIN TO YOUR ACCOUNT

Username
Password
Remember Me
Or use your Academic/Social account:

CREATE AN ACCOUNT

Or use your Academic/Social account:

Congratulations!

You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.

Important!

Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message

CREATE AN ACCOUNT

Name:
Username:
Password:
Verify Password:
E-mail:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Tahmassebi, JF; Chrysafi, N; Duggal, MS (2014)
Publisher: Elsevier
Languages: English
Types: Article
Subjects:
Objective: This study investigated the effect of ozone on the progression or regression of artificial caries-like lesions on enamel following pH cycling conditions in vitro. Methods: A randomized, single blind, four legs design was used. 20 full thickness enamel slabs were allocated to each of the four groups which were: Fluoride free toothpaste (control); ozone alone; Reductant/Patient Kit alone and a combination of both ozone/Reductant/Patient Kit. Artificial lesions were created and subjected to the pH cycling regime for a 14 days period. Assessments were carried out before and after the pH cycling on the slabs using the microhardness testing and Quantitative Light-induced Fluorescence (QLF). Results: Statistical significant difference were found in the percentage change of enamel microhardness before and after pH cycling between ozone/Reductant/Patient Kit group and all the other three groups of the study, as well as between Reductant/Patient Kit group and control. There was a statistical significant difference in the change of size and severity of the lesion (ΔQ) between all the three regimes tested and the control with a trend favouring ozone/Reductant/Patient Kit group. Conclusions: In our model, it appeared that ozone treatment alone is not effective in protecting the enamel against demineralisation or promoting remineralisation, unless combined with the Reductant/Patient Kit, which contain high levels of fluoride.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1. Holmes J. Clinical reversal of root caries using Ozone, double-blind randomized controlled 18- month trial. Gerodont 2003; 20(2):106-114
    • 2. Lynch E. Ozone: the revolution in dentistry. Quintessence Publishing Co. Ltd; 2004
    • 3. Baysan A, Whiley RA, Lynch E. Antimicrobial effect of a novel Ozonegenerating device on micro-organisms associated with primary root carious lesions in vitro. Caries Res 2000; 34:498-501
    • 4. Baysan A, Lynch E. Effect of Ozone on the oral microbiota and clinical severity of primary root caries. Am J Dent 2004; 17:56-60
    • 5. Abu-Salem O. Reversal of occlusal caries in primary teeth. MPhil Thesis: Queen's University Belfast; 2004
    • 6. Abu-Naba'a L.A. Management of primary occlusal pit and fissure caries using Ozone. PhD Thesis: Queen's University Belfast; 2003
    • 7. Baysan A, Beighton D. Assessment of the Ozone-mediated killing of bacteria in infected dentine associated with non-cavitated occlusal carious lesions. Caries Res 2007; 41(5):337-341
    • 8. Duggal MS, Nikolopoulou A, Tahmassebi JF. The additional effect of ozone in combination with adjunct remineralisation products on inhibition of demineralization of the dental hard tissue in situ. J Dent 2012; 40:934-940
    • 9. Rickard GD, Richardson R, Johnson T, McColl D, Hooper L. Ozone therapy for the treatment of dental caries. The Cochrane Database of Systematic Reviews, Issue 3 2004; DOI:10.1002/14651858.CD0041
    • 10. Brazzelli M, McKenzie L, Fielding S, Fraser C, Clarkson J, Kilonzo M, Waugh N. Systematic review of the effectiveness and cost-effectiveness of HealOzone for the treatment of occlusal pit/fissure caries and root caries. Healt Technol Asses 2006; 10(16):iii-iv, ix-80
    • 11. Al-Mullahi AM. Effect of slow-release fluoride devices and caseinphosphopeptide nanocomplexes on enamel remineralisation in vitro. MDenSci Thesis: University of Leeds, Leeds; 2008
    • 12. Zero DT, Fu J, Anne KM, Cassata S, McCormack SM, Gwinner LM. An improved intra-oral enamel demineralization test model for the study of dental caries. J Dent Res 1992; 71:872-878
  • No related research data.
  • No similar publications.

Share - Bookmark

Cite this article