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fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Urwin, Samuel
Languages: English
Types: Doctoral thesis
Subjects: B900, B800

Classified by OpenAIRE into

mesheuropmc: human activities, musculoskeletal diseases
In total knee replacement (TKR) surgery, mobile bearing (MB) total knee prostheses were designed to more closely mimic the function of the normal knee than traditional fixed bearing (FB) designs by allowing axial mobility between the polyethylene insert and tibial tray. Despite the hypothetical benefits of the MB design, few studies have objectively analysed knee biomechanics during activities of daily living (ADLs) in the laboratory compared to FB designs. This thesis aimed to substantiate the theoretical advantages of MB implantation during ADLs in the laboratory as well as during free living conditions, in addition to investigating previous claims of instability in MB knees. Sixteen patients undergoing primary unilateral total knee replacement (TKR) surgery were randomised to receive either a FB (n=8) or MB (n=8) total knee prosthesis and were tested at pre-surgery, three months post-surgery, and nine months post-surgery using three dimensional motion analysis in the laboratory and electrogoniometry and accelerometry during free living conditions. No differences were found between FB and MB groups during walking at post-surgery that could not be explained by differences at pre-surgery. There were also no differences between FB and MB groups during the more biomechanically demanding activities of stair negotiation and sit to stand and stand to sit activities, as well as no differences during free living conditions away from the laboratory. There appears to be no evidence based rationale for the widespread use of MBs with regards to optimising knee function during ADLs. This thesis was the first to compare FB and MB designs using the same implant range, posterior cruciate ligament (PCL) scenario, posterior stabilising strategy, and patella strategy over a range of ADLs, as well as being the first to combine testing in the laboratory with testing during free living conditions away from the laboratory.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1.1 Development of total knee prostheses............................................................20
    • 1.2 Theoretical basis for mobile bearing total knee prostheses and rationale for
    • further research.....................................................................................................22
    • 1.3 Aims of this thesis ..........................................................................................25
    • 1.4 Objectives of this thesis..................................................................................25
    • 1.5 Synopsis of this thesis ....................................................................................26 2.0 Literature review..............................................................................................................28 3.1 Ethical approval..............................................................................................48 3.2 Set-up of the three dimensional motion analysis system ...............................49
    • 3.2.1 Activities of daily living protocol used in the three dimensional motion analysis
    • system ..........................................................................................................................53
    • 3.2.2 Data cleaning and processing in the three dimensional motion analysis system 55 3.3 Electrogoniometry and accelerometry systems ..............................................57
    • 3.3.1 Ambulatory protocol used in the electrogoniometry and accelerometry systems
    • for testing away from the laboratory............................................................................61
    • 3.3.2 Data cleaning and processing in the electrogoniometry and accelerometry
    • systems.........................................................................................................................62 3.4 Total knee replacement procedure .................................................................66
    • 9.1 Key findings from this thesis........................................................................217
    • 9.2 Discussion of key findings ...........................................................................217
    • 9.3 Original contributions to knowledge ............................................................222
    • 9.4 Limitations....................................................................................................223
  • No related research data.
  • No similar publications.

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