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Wagstaff, Jane L.; Vallath, Sabari; Marshall, John F.; Williamson, Richard A.; Howard, Mark J. (2010)
Languages: English
Types: Article
Subjects: QD, QH301, TP
We report the first example of peptide-protein heteronuclear two-dimensional (2D) saturation transfer difference nuclear magnetic resonance (STD NMR). This method, resulting in dramatically reduced overlap, was applied to the interaction of the integrin alphavbeta6 with a known peptide ligand and highlights novel contact points between the substrate and target protein.

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