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fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Crabbe, A; Thompson, P (2004)
Publisher: Lippincott Williams & Wilkins
Languages: English
Types: Article
Subjects:
Purpose. To test the design of a patient care regimen for soft lenses that aims to provide the highest standards of disinfecting through use of domestic microwave cookers, while also providing storage equipment and solution that enable patients to follow a conventional cold disinfecting regimen when traveling. The cleaning efficacy of surfactant agents during microwave treatment was also considered. Methods. The microbiologic performance of the regimen and its disinfecting apparatus was tested according to the Food and Drug Administration (FDA) protocols for contact lens heat disinfectors. Subsequently, a prospective pilot clinical trial of the regimen involving 15 subjects was carried out to the protocols of the FDA and International Standards Organization 11,980:1997. Results. Lenses inoculated with 107 colony-forming units (cfu) of Enterococcus faecalis were disinfected to 0 cfu by a 12-s irradiation of a compact disinfecting case that held the lenses suspended in 12 ml saline. A proof of operation indicator performed correctly for all 10 cases tested. No adverse reactions were found in the pilot patient trial, using Renu multipurpose (Bausch & Lomb, Rochester, NY) as the test solution, and no statistically significant difference was found between test and control groups in respect of any sign. However, the greater incidence of edema, palpebral hyperemia, and lens front-surface deposition in the microwave test group may be clinically significant.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1. Association of Contact Lens Manufacturers (UK) Market Trends 2002, unpublished internal bulletin.
    • 2. Crabbe A, Thompson P. Clinical trial of a patient-operated microwave care system for hydrogel contact lenses. Optom Vis Sci 2001; 78:605-9.
    • 3. Hiti K, Walochnik J, Faschinger C, Haller-Schober EM, Aspock H. Microwave treatment of contact lens cases contaminated with acanthamoeba. Cornea 2001;20:467-70.
    • 4. Harris MG, Rechberger J, Grant T, Holden BA. In-office microwave disinfection of soft contact lenses. Optom Vis Sci 1990;67:129-32.
    • 5. US Department of Health and Human Services, Food and Drug Administration, Center for Devices and Radiological Health. Premarket Notification (510k) Guidance Document for Contact Lens Care Products, 1997. Available at: http://www.fda.gov/cdrh/ode/ contlens.pdf. Accessed February 13, 2004:38-40, 43-5.
    • 6. Merindano MD, Marqués S, Lluch M, Gonzàles M, Saona C. Domestic microwave oven in contact lens disinfection. Contact Lens J 1990;18:241-6.
    • 7. Quesnel N, Simonet P, Giasson C. Stability of Crofilcon and Polymacon (clear and tinted) contact lenses after microwave irradiation. J Br Contact Lens Assoc 1996;19:49-54.
    • 8. Crabbe A, Thompson P. Effects of microwave irradiation on the parameters of hydrogel contact lenses. Optom Vis Sci 2001;78: 610-5.
    • 9. Claydon BE, Efron N. Non-compliance in contact lens wear. Ophthalmic Physiol Opt 1994;14:356-64.
    • 10. International Organization for Standardization. ISO 11980:1997: Ophthalmic Optics-Contact Lenses and Contact Lens Care Products-Guidance for Clinical Investigators. Geneva: International Organization for Standardization, 1997.
    • 11. Center for Devices and Radiological Health. Premarket Notification (510k) Guidance Document for Contact Lens Care Products, 1997. Available at: http://www.fda.gov/cdrh/ode/contlens.pdf. Accessed February 13, 2004:43.
    • 12. Russell AD, Hugo WB, Ayliffe GAJ, Principles and Practice of Disinfection, Preservation and Sterilization. 2nd ed. Oxford: Blackwell Scientific Publications, 1992.
    • 13. Kilvington S. Acanthamoeba trophozoite and cyst adherence to four types of soft contact lens and removal by cleaning agents. Eye 1993; 7:535-8.
    • 14. Center for Devices and Radiological Health. Premarket Notification (510k) Guidance Document for Contact Lens Care Products, 1997. Available at: http://www.fda.gov/cdrh/ode/contlens.pdf. Accessed February 13, 2004:44, 94-8.
    • 15. Riedhammer TM, Falcetta JJ. Effects of long-term heat disinfection on Soflens (polymacon) contact lenses. J Am Optom Assoc 1980;51: 287-9.
    • 16. Hawley GG, Lewis RJ. Hawley's Condensed Chemical Dictionary. 14th ed. on CD-ROM. New York: Wiley, 2002.
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