LOGIN TO YOUR ACCOUNT

Username
Password
Remember Me
Or use your Academic/Social account:

CREATE AN ACCOUNT

Or use your Academic/Social account:

Congratulations!

You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.

Important!

Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message

CREATE AN ACCOUNT

Name:
Username:
Password:
Verify Password:
E-mail:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Parker, Amanda; Wilding, Edward Lewis; Akerman, Colin (1998)
Publisher: MIT Press
Languages: English
Types: Article
Subjects:

Classified by OpenAIRE into

mesheuropmc: genetic structures
This study reports the development of a new, modified delayed matching to sample (DMS) visual recognition memory task that controls the relative novelty of test stimuli and can be used in human and nonhuman primates. We report findings from normal humans and unoperated monkeys, as well as three groups of operated monkeys. In the study phase of this modified paradigm, subjects studied lists of two-dimensional visual object stimuli. In the test phase each studied object was presented again, now paired with a new stimulus (a foil), and the subject had to choose the studied item. In some lists one study item (the novel or isolate item) and its associated foil differed from the others (the homogenous items) along one stimulus dimension (color). The critical experimental measure was the comparison of the visual object recognition error rates for isolate and homogenous test items.\ud \ud This task was initially administered to human subjects and unoperated monkeys. Error rates for both groups were reliably lower for isolate than for homogenous stimuli in the same list position (the von Restorff effect). The task was then administered to three groups of monkeys who had selective brain lesions. Monkeys with bilateral lesions of the amygdala and fornix, two structures that have been proposed to play a role in novelty and memory encoding, were similar to normal monkeys in their performance on this task. Two further groups— with disconnection lesions of the perirhinal cortex and either the prefrontal cortex or the magnocellular mediodorsal thalamus—showed no evidence of a von Restorff effect. These findings are not consistent with previous proposals that the hippocampus and amygdala constitute a general novelty processing network. Instead, the results support an interaction between the perirhinal and frontal cortices in the processing of certain kinds of novel information that support visual object recognition memory.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • Bachevalier, J., & Mishkin, M. (1986). Visual recognition impairment follows ventromedial but not dorsolateral prefrontal lesions in monkeys. Behavioral Brain Research, 20, 249-261.
    • Brown, M. W. (1996). Neuronal responses and recognition memory. Seminars in the Neurosciences, 8, 23-32.
    • Brown, M. W., Wilson, F. A.W., & Riches, I. P. (1987). Neuronal evidence that inferomedial temporal cortex is more important than hippocampus in certain processes underlying recognition memory. Brain Research, 409, 158-162.
    • Buckley, M. J., & Gaffan, D. (1997). Impairment of visual object-discrimination learning after perirhinal cortex ablation. Behavioral Neuroscience, 111, 467-475.
    • Buckley, M. J., Gaffan, D., & Murray, E. A. (1997). A functional double-dissociation between two inferior temporal cortical areas: Perirhinal cortex versus middle temporal gyrus. Journal of Neurophysiology, 77, 587-598.
    • Dolan, R. J., & Fletcher, P. C. (1997). Dissociating prefrontal and hippocampal function in episodic memory encoding. Nature, 388, 582-585.
    • Fahy, F. L., Riches, I. P., & Brown, M. W. (1993). Neuronal activity related to visual recognition memory: Long-term memory and the encoding of recency and familiarity information in the primate anterior and medial inferior temporal and rhinal cortex. Experimental Brain Research, 96, 457-472.
    • Gaffan, D., & Murray, E. A. (1990). Amygdalar interaction with the mediodorsal nucleus of the thalamus and the ventromedial prefrontal cortex in stimulus-reward associative learning. Journal of Neuroscience, 10, 3479-3493.
    • Hunt, R. R. (1995). The subtlety of distinctiveness: What von Restorff really did. Psychonomic Bulletin & Review, 2, 105-112.
    • Knight, R. T. (1984). Decreased response to novel stimuli after prefrontal lesions in man. Electroencephalography and Clinical Neurophysiology 59, 9-20.
    • Knight, R. T. (1996). Contribution of hippocampal region to novelty detection. Nature, 383, 256-259.
    • Mandler, G. (1980). Recognizing: The judgment of previous occurrence. Psychological Review, 87, 252-271.
    • Metcalfe, J. (1993). Novelty monitoring, metacognition and control in a composite holographic associative recall model: Implications for Korsakoff amnesia. Psychological Review, 100, 3-22.
    • Metcalfe, J. (1994a). Monitoring and gain control in an episodic memory model: Relation to P300 event-related potential. In A. F. Collins, M. A. Conway, S. E. Gathercole, & P. E. Morris (Eds.), Theories of memory (pp. 163-188). Hillsdale, N.J.: Erlbaum.
    • Metcalfe, J. (1994b). A computational modeling approach to novelty monitoring, metacognition, and frontal lobe dysfunction. In J. Metcalfe & A. P. Shimamura (Eds.), Metacognition: Knowing about knowing (pp. 137-156). Cambridge, MA: MIT Press.
    • Meunier, M., Bachevalier, J., & Mishkin, M. (1997). Effects of orbital frontal and anterior cingulate lesions on object and spatial memory in rhesus monkeys. Neuropsychologia, 35, 999-1015.
    • Meunier, M., Bachevalier, J., Mishkin, M., & Murray, E. A. (1993). Effects on visual recognition of combined and separate ablations in the entorhinal and perirhinal cortex in rhesus monkeys. Journal of Neuroscience, 13, 5418-5432.
    • Parker, A., & Gaffan, D. (1998). Interaction of frontal and perirhinal cortices in visual object recognition memory in monkeys. European Journal of Neuroscience, 10, pp. 3044-3058.
    • Riches, I. P., Wilson, F. A. W., & Brown, M. W. (1991). The effects of visual stimulation and memory on neurons of the hippocampal formation and the neighboring parahippocampal gyrus and inferior temporal cortex of the primate. Journal of Neuroscience, 11, 1763-1779.
    • Rolls, E. T., Cahusac, P. M. B., Feigenbaum, J. D., & Miyashita, Y. (1993). Responses of single neurons in the hippocampus of the macaque related to recognition memory. Experimental Brain Research, 93, 299-306.
    • Saltz, E., & Newman, S. E. (1959). The von Restorff isolation effect: Test of the intralist association assumption. Journal of Experimental Psychology, 58, 445-451.
    • Snedecor, G. W., & Cochran, W. G. (1967). Statistical methods. Ames, Iowa: Iowa State Univ. Press.
    • Shimamura, A. P., Janowsky, J. S., & Squire, L. R. (1991). What is the role of frontal lobe damage in memory disorders? In H. S. Levin, H. M. E. Benberg, & A. L. Benton (Eds.), Frontal lobe function and dysfunction (pp. 173-195). Oxford, UK: Oxford University Press.
    • Tulving, E., & Markowitsch, H. J. (1997). Memory beyond the hippocampus. Current Opinion in Neurobiology, 7, 209- 216.
    • Tulving, E., Markowitsch, H. J., Craik, F. I. M., Habib, R. H., & Houle, S. (1996). Novelty and familiarity activations in PET studies of memory encoding and retrieval. Cerebral Cortex, 6, 71-79.
    • Tulving, E., Markowitsch, H. J., Kapur, S., Habib, R., & Houle, S. (1994). Novelty encoding networks in the human brain: Positron emission tomography data. Neuroreport, 5, 2525- 2528.
    • von Restorff, H. (1933). Uber die wirkung von bereichsbildungen im spurenfeld [On the effect of spheres formations in the trace ªeld]. Psychologische Forschung, 18, 299-342.
    • Wallace, W. P. (1965). Review of the historical, empirical and theoretical status of the von Restorff phenomenon. Psychological Bulletin, 63, 410-424.
    • Williams, G. V., Rolls, E. T., Leonard, C. M., & Stern, C. (1993). Neuronal responses in the ventral striatum of the behaving macaque. Behavioral Brain Research, 55, 243-252.
    • Wilson, F. A. W., & Rolls, E. T. (1993). The effects of stimulus novelty and familiarity on neuronal activity in the amygdala of monkeys performing recognition memory tasks. Experimental Brain Research, 93, 367-382.
    • Wise, S. P., Murray, E. A., & Gerfen, C. R. (1996). The frontal cortex-basal ganglia system in primates. Critical Reviews in Neurobiology, 10, 317-356.
  • No related research data.
  • Discovered through pilot similarity algorithms. Send us your feedback.

Share - Bookmark

Cite this article