LOGIN TO YOUR ACCOUNT

Username
Password
Remember Me
Or use your Academic/Social account:

CREATE AN ACCOUNT

Or use your Academic/Social account:

Congratulations!

You have just completed your registration at OpenAire.

Before you can login to the site, you will need to activate your account. An e-mail will be sent to you with the proper instructions.

Important!

Please note that this site is currently undergoing Beta testing.
Any new content you create is not guaranteed to be present to the final version of the site upon release.

Thank you for your patience,
OpenAire Dev Team.

Close This Message

CREATE AN ACCOUNT

Name:
Username:
Password:
Verify Password:
E-mail:
Verify E-mail:
*All Fields Are Required.
Please Verify You Are Human:
fbtwitterlinkedinvimeoflicker grey 14rssslideshare1
Helm, J.; McBrearty, A.; Fontaine, S.; Morrison, R.; Yam, P. (2016)
Publisher: Wiley
Languages: English
Types: Article
Subjects:
Objectives:\ud To perform a preliminary study to assess whether single-agent palliative or adjuvant chemotherapy has an impact on objectively measured physical activity in dogs.\ud \ud Methods:\ud Fifteen dogs with neoplasia (treatment group) wore ActiGraphâ„¢ accelerometers for 5-day periods before, during and after receiving single-agent adjuvant or palliative chemotherapy. Mean 5-day total physical activity and time spent in three different intensities of activity (sedentary, light-moderate and vigorous) before, during and after receiving chemotherapy were compared to a group of 15 healthy dogs (control group). Results were also compared within the treatment group across time.\ud \ud Results:\ud Prior to chemotherapy, treated dogs tended to be less active than control dogs. Treatment group dogs were slightly more active at restaging than they were prior to treatment but had similar activity levels to control dogs. Marked effects of chemotherapy on physical activity were not detected. Physical activity was slightly lower in treated dogs during chemotherapy when compared to control dogs but there was a slight increase in physical activity of treated dogs during chemotherapy when compared with pretreatment recordings. There was little change in the mean 5-day total physical activity between treated dogs during chemotherapy and at restaging but a mild decrease in time spent sedentary and increase in time spent in light-moderate activity at this comparison of time points.\ud \ud Clinical Significance:\ud Single-agent adjuvant or palliative chemotherapy had minimal impact on physical activity levels in dogs with neoplasia.
  • The results below are discovered through our pilot algorithms. Let us know how we are doing!

    • 1. Aaronson, N.K, Ahmedzai, S., Bergman, B. et al. (1993) The European Organization for Research and Treatment of Cancer QLQ-C30: A quality of life instrument for use in international clinical trials in oncology. Journal of the National Cancer Institute 85, 365-376
    • 2. ActiGraphTM (2013) https://help.theactigraph.com/entries/22041532 [accessed 4 May 2016]
    • 3. Backman, M., Wengstrom, Y., Johansson, B., et al. (2014) A randomized pilot study with daily walking during adjuvant chemotherapy for patients with breast and colorectal cancer. Acta Oncologica 53, 510-520
    • 4. Bowles, D. B., Robson, N. M. C., Galloway, P. E., et al. (2010) Owners' perception of carboplatin in conjunction with other palliative treatments for cancer therapy Journal of Small Animal Practice 51, 104-112
    • 5. Carrison, M. and Hamrin, E. (1996) Measurement of quality of life in women with breast cancer. Development of a Life Satisfaction Questionnaire (LSQ-32) and a comparison with the EORTC QLQ-C30. Quality of Life Research 5, 265-274
    • 6. Corder, K., Ekelund, U., Steele, R.M., et al. (2008) Assessment of physical activity in youth. Journal of applied Physiology 105 977-987
    • 7. De Vries, S. I., Van Hirtum, H. W., Bakker, I. et al. (2009) Validity and reproducibility of motion sensors in youth: a systematic update. Medicine and Science in Sports and Exercise 41, 818-827
    • 8. Durante, R. and Ainsworth, B. E. (1996) The recall of physical activity: using a cognitive model of the question-answering process. Medicine and Science in Sports and Exercise 28, 1282-91
    • 9. Ehrhart, N.P., Ryan, S.D., & Fan, T.M. (2013) Tumors of the Skeletal System. In: Textbook of Small Animal Clinical Oncology. 5th edn. Eds S.J. Withrow, D.M. Vail and R.L. Page. Elsevier Saunders, Missouri. pp 482-483
    • 10. Fox, L. E., Rosenthal, R. C., King, R. R., et al. (2000) Use of cis-bis-neodecanoatotrans-R,R-1,2-diaminocyclohexane platinum (II), a liposomal cisplatin analogue, in cats with oral squamous cell carcinoma. American Journal of Veterinary Research 61, 791-795
    • 11. Gunnars, B., Nygren, P., Glimelius, B., et al. (2001) Assessment of Quality of Life during Chemotherapy. Acta Oncologica 40, 175-184
    • 12. Iliopoulou, M.A., Kitchell, B.E., Yuzbasiyan-Gurkan, Y. et al. (2013) Development of a survey instrument to assess health-related quality of life in small animal cancer patients treated with chemotherapy. Journal of the American Veterinary Medical Association 242 1679-1687
    • 13. Kriska, A.M. and Caspersen, C.J. (1997) Introduction to a collection of physical activity questionnaires. Medicine and Science in Sports and Exercise 29, 5-9
    • 14. London, C.A., Malpas, P.B., Wood-Follis, S.L., et al. (2009) Multi-center, placebocontrolled, double-blind, randomized study of oral toceranib phosphate (SU11654), a receptor tyrosine kinase inhibitor, for the treatment of dogs with recurrent (either local or distant) mast cell tumor following surgical excision. Clinical Cancer Research 15, 3856-3865
    • 15. Lowe, S.S., Danielson, B., Watanabe, S.M., et al. (2014) Associations between objectively measured physical activity and quality of life in cancer patients with brain metastases. Journal of Pain and Symptom Management 48, 322-332
    • 16. Lucroy, M.D., Phillips, B.S., Kraegel, S.A., et al. (1998) Evaluation of single-agent mitoxantrone as chemotherapy for relapsing canine lymphoma. Journal of Veterinary Internal Medicine 12, 325-329
    • 17. Lynch, S., Savary-Bataille, K., Leeuw, B., et al. (2011) Development of a questionnaire assessing health-related quality-of-life in dogs and cats with cancer. Veterinary and Comparative Oncology 9, 172-182
    • 18. Malik, R., Gabor, L.J., Foster, S.F., et al. (2001) Therapy for Australian cats with lymphosarcoma. Australian Veterinary Journal 79, 808-817
    • 19. Marrington, A.M., Killick, D.R., Grant, I.A., et al. (2012) Toxicity associated with epirubicin treatments in a large case series of dogs Veterinary and Comparative Oncology 10, 113-123
    • 20. McMillan, F.D. (2000) Quality of life in animals. Journal of the American Veterinary Medical Association 216 1904 - 1910
    • 21. Mellanby R. J., Herttage, M. E. & Dobson, J. M. (2003) Owners' assessments of their dog's quality of life during palliative chemotherapy for lymphoma. Journal of Small Animal Practice 44, 100-103
    • 22. Morrison, R., Penpraze, V., Berber, A., et al. (2013a). Associations between obesity and physical activity in dogs: a preliminary investigation. Journal of Small Animal Practice 54, 570-4
    • 23. Morrison, R., Reilly, J.J., Penpraze, V., et al. (2013b). Children, parents and pets exercising together (CPET): exploratory randomised controlled trial. BMC Public Health 13, 1096
    • 24. Morrison, R., Penpraze, V., Greening, R., et al. (2014). Correlates of objectively measured physical activity in dogs. The Veterinary Journal 199, 263-7
    • 25. Olgilvie, G.K., Vail, D.M., Klein, M.K. et al. (1991) Weekly administration of lowdose doxorubicin for treatment of malignant lymphoma in dogs. Journal of the American Veterinary Medical Association 198, 1762-1764
    • 26. Reilly, J.J., Penpraze, V., Hislop, J., et al. (2008) Objective measurement of physical activity and sedentary behaviour: review with new data. Archives of Disease in Childhood 93, 614 - 619
    • 27. Rivera, P., Akerlund-Denneberg, N., Bergvall, K., et al. (2013) Clinical efficacy and safety of a water-solube micellar paclitaxel (Paccal Vet) in canine mastocytomas. Journal of Small Animal Practice 54, 20-27
    • 28. Robusto, K.M., and Trost, S.G. (2012) Comparison of three generations of ActiGraphâ„¢ activity monitors in children and adolescents. The Journal of Sports Science. 30 1429-1435
    • 29. Sirard, J. R. and Pate, R. R. (2001) Physical activity assessment in children and adolescents. Sports Medicine 31, 439-54
    • 30. Skerman, H.M., Yates, P.M., & Battistutta, D. (2012) Cancer-related symptom clusters for symptom management in outpatients after commencing adjuvant chemotherapy, at 6 months, and 12 months. Supportive Care in Cancer 20, 95-105
    • 31. Slater, M.R., Barto, C.L., Rogers, K.S., et al. (1996) Factors affecting treatment decisions and satisfaction of owners of cats with cancer. Journal of the American Veterinary Medical Association 208, 1248-1252
    • 32. Spitzer, W.O., Dobson, A.J., Hall, J., et al. (1981) Measuring the quality of life of cancer patients: a concise QL-index for use by physicians. Journal of Chronic Disease 34, 585-597
    • 33. Sprangers, M. A. G., (2002) Quality of life assessment in oncology. Acta Oncologica 41, 229-237
    • 34. Tan, S.Y., Poh, B. K., Chong, H.X., et al. (2013) Physical activity of pediatric patients with acute leukemia undergoing induction or consolidation chemotherapy. Leukemia Research 37, 14-20
    • 35. Tzannes, S., Hammond, M. F., Murphy, S., et al. (2008) Owners 'perception of their cats' quality of life during COP chemotherapy for lymphoma. Journal of Feline Medicine and Surgery 10, 73-81
    • 36. Vermaete, N., Wolter, P., Verhoef, G., et al. (2014) Physical activity and physical fitness in lymphoma patients before, during, and after chemotherapy: a prospective longitudinal study. Annals of Hematology 93, 211-424 Yam, P.S., Penpraze, V., Young, D., et al. (2011) Validity, practical utility and reliability of Actigraph accelerometry for the measurement of habitual physical activity in dogs. Journal of Small Animal Practice 52, 86-91 38. Yeates, J., and Main, D. (2009) Assessment of companion animal quality of life in veterinary practice and research. Journal of Small Animal Practice 50, 274 - 281
  • No related research data.
  • No similar publications.

Share - Bookmark

Download from

Cite this article